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HTR2A 5-hydroxytryptamine receptor 2A [ Pan troglodytes (chimpanzee) ]

Gene ID: 467355, updated on 29-Mar-2024

Summary

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Official Symbol
HTR2Aprovided by VGNC
Official Full Name
5-hydroxytryptamine receptor 2Aprovided by VGNC
Primary source
VGNC:VGNC:9791
Locus tag
CK820_G0049599
See related
Ensembl:ENSPTRG00000005858
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 14 NC_072412.2 (52425035..52490461, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 13 NC_072411.1 (47791821..47858353, complement)

Chromosome 14 - NC_072412.2Genomic Context describing neighboring genes Neighboring gene leucine rich repeats and calponin homology domain containing 1 Neighboring gene uncharacterized LOC104001829 Neighboring gene esterase D Neighboring gene uncharacterized LOC134808194 Neighboring gene guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Heterogeneous rate of protein evolution in serotonin genes. Andrés AM, et al. Mol Biol Evol, 2007 Dec. PMID 17884826
  2. Human-specific amino acid changes found in 103 protein-coding genes. Kitano T, et al. Mol Biol Evol, 2004 May. PMID 15014171

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to xenobiotic stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-hydroxytryptamine receptor 2A
Names
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072412.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    52425035..52490461 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_522752.9 → XP_522752.2  5-hydroxytryptamine receptor 2A isoform X1

    See identical proteins and their annotated locations for XP_522752.2

    UniProtKB/TrEMBL
    A0A2J8J9Q7, A0A6D2WYI0, H2Q7J6
    Related
    ENSPTRP00000009967.3
    Conserved Domains (1) summary
    cd15304
    Location:75 → 391
    7tmA_5-HT2A; serotonin receptor subtype 2A, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_003314137.7 → XP_003314185.1  5-hydroxytryptamine receptor 2A isoform X2

    See identical proteins and their annotated locations for XP_003314185.1

    UniProtKB/TrEMBL
    A0A2I3TGC7, A0A2J8J9R1, A0A6D2WUZ5
    Related
    ENSPTRP00000088301.1
    Conserved Domains (2) summary
    cd14964
    Location:65 → 87
    7tm_GPCRs; TM helix 3 [structural motif]
    cl28897
    Location:55 → 307
    7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
Nucleotide Protein
Heading Accession and Version

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