PPP2R1B protein phosphatase 2 scaffold subunit Abeta [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PPP2R1Bprovided by VGNC
Official Full Name: protein phosphatase 2 scaffold subunit Abetaprovided by VGNC
Primary source: VGNC:VGNC:10399
Locus tag: CK820_G0034403
See related: Ensembl:ENSPTRG00000004270
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: SIK2
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	9	NC_072407.2 (113707641..113750274, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	11	NC_072409.1 (112929860..112972475, complement)

Chromosome 9 - NC_072407.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

WI-11653 (e-PCR)
- UniSTS:6944

STS-H27731 (e-PCR)
- UniSTS:7716

D8S2279 (e-PCR)
- UniSTS:473907

RH92519 (e-PCR)
- UniSTS:87883

STS-F04139 (e-PCR)
- UniSTS:24672

D11S4338 (e-PCR)
- UniSTS:39023

D15S1477 (e-PCR)
- UniSTS:474482

D1S1423 (e-PCR)
- UniSTS:149619

RH69258 (e-PCR)
- UniSTS:68783

SHGC-78624 (e-PCR)
- UniSTS:102080

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein phosphatase regulator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein dephosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
part_of protein phosphatase type 2A complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

Names: protein phosphatase 2, regulatory subunit A, beta; salt-inducible kinase 2

NP_001267102.1

EC 3.1.3.16

XP_009422348.2

EC 3.1.3.16

XP_009422349.2

EC 3.1.3.16

XP_009422350.2

EC 3.1.3.16

XP_016775360.2

EC 3.1.3.16

XP_016775361.2

EC 3.1.3.16

XP_024202594.2

EC 3.1.3.16

XP_063638651.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001280173.1 → NP_001267102.1 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

See identical proteins and their annotated locations for NP_001267102.1

Status: PROVISIONAL

Source sequence(s)

AK306948

UniProtKB/TrEMBL

A0A2I3RMI1, A0A2J8L0F4, A0A6D2WZR9, G2HJN4

Related

ENSPTRP00000007340.4, ENSPTRT00000007953.5

Conserved Domains (3) summary

pfam13646
Location:217 → 316

HEAT_2; HEAT repeats

sd00044
Location:257 → 281

HEAT; HEAT repeat [structural motif]

cl21454
Location:408 → 466

NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

113707641..113750274 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016919871.4 → XP_016775360.2 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1
XM_016919872.3 → XP_016775361.2 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X3
XM_063782581.1 → XP_063638651.1 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X5
XM_009424073.5 → XP_009422348.2 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2
XM_024346826.3 → XP_024202594.2 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X7
XM_009424074.5 → XP_009422349.2 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X4

UniProtKB/TrEMBL

A0A2J8L0E9, A0A6D2XW29, K7CWZ7
XM_009424075.5 → XP_009422350.2 serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X6

UniProtKB/TrEMBL

A0A2I3SYL6, A0A2J8L0F8, A0A6D2WGN3