HRAS HRas proto-oncogene, GTPase [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: HRASprovided by VGNC
Official Full Name: HRas proto-oncogene, GTPaseprovided by VGNC
Primary source: VGNC:VGNC:50562
Locus tag: CK820_G0044165
See related: Ensembl:ENSPTRG00000034469
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	9	NC_072407.2 (4731820..4735113, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	11	NC_072409.1 (4648663..4651981, complement)

Chromosome 9 - NC_072407.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

PMC33481P1 (e-PCR)
- UniSTS:273164

GDB:177543 (e-PCR)
- UniSTS:154922

PMC152554P1 (e-PCR)
- UniSTS:271231

PMC152554P2 (e-PCR)
- UniSTS:271232

GDB:187026 (e-PCR)
- UniSTS:155536

G29883 (e-PCR)
- UniSTS:64957

HRAS (e-PCR), detects polymorphism
- UniSTS:64703

RH75826 (e-PCR)
- UniSTS:90048

GDB:177373 (e-PCR)
- UniSTS:154870

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GDP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Ras protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular senescence	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: GTPase HRas

Names: v-Ha-ras Harvey rat sarcoma viral oncogene homolog

XP_016775457.1

EC 3.6.5.3

XP_016775458.1

EC 3.6.5.3

XP_063639697.1

EC 3.6.5.3

XP_063639698.1

EC 3.6.5.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

4731820..4735113 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016919968.4 → XP_016775457.1 GTPase HRas isoform X1

UniProtKB/TrEMBL

A0A2J8JVW1, A0A6D2WZH5, H2Q2V0, K7ALD7

Related

ENSPTRP00000005495.5

Conserved Domains (1) summary

cd04138
Location:3 → 164

H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B
XM_063783628.1 → XP_063639698.1 GTPase HRas isoform X3
XM_063783627.1 → XP_063639697.1 GTPase HRas isoform X2

UniProtKB/TrEMBL

A0A2I3S349, A0A2J8JVW2, A0A6D2Y284
XM_016919969.4 → XP_016775458.1 GTPase HRas isoform X2

UniProtKB/TrEMBL

A0A2I3S349, A0A2J8JVW2, A0A6D2Y284, H2Q5M1

Related

ENSPTRP00000071354.1

Conserved Domains (1) summary

cd04138
Location:3 → 150

H_N_K_Ras_like; Ras GTPase family containing H-Ras,N-Ras and K-Ras4A/4B