ADRA2A adrenoceptor alpha 2A [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ADRA2Aprovided by VGNC
Official Full Name: adrenoceptor alpha 2Aprovided by VGNC
Primary source: VGNC:VGNC:3798
Locus tag: CK820_G0003953
See related: Ensembl:ENSPTRG00000029720
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	8	NC_072406.2 (123196876..123200137)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	10	NC_072408.1 (113813759..113817020)

Chromosome 8 - NC_072406.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

SHGC-147233 (e-PCR)
- UniSTS:175690

STS-AA040321 (e-PCR)
- UniSTS:40025

GDB:193856 (e-PCR)
- UniSTS:155764

D10S1861 (e-PCR)
- UniSTS:39286

ADRA2A__4205 (e-PCR)
- UniSTS:462716

RH93859 (e-PCR)
- UniSTS:87259

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables alpha2-adrenergic receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables epinephrine binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in platelet activation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of smooth muscle contraction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of vasoconstriction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alpha-2A adrenergic receptor

Names: adrenergic, alpha-2A-, receptor; alpha-2A-adrenergic receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

123196876..123200137

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003312765.4 → XP_003312813.2 alpha-2A adrenergic receptor

UniProtKB/TrEMBL

A0A2J8PCL0, A0A6D2W063, H2RIK3, K7BR90

Related

ENSPTRP00000061362.2

Conserved Domains (2) summary

cd15322
Location:49 → 452

7tmA_alpha2A_AR; alpha-2 adrenergic receptors subtype A, member of the class A family of seven-transmembrane G protein-coupled receptors

cl28033
Location:240 → 389

Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region