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F9 coagulation factor IX [ Pan troglodytes (chimpanzee) ]

Gene ID: 465887, updated on 29-Mar-2024

Summary

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Official Symbol
F9provided by VGNC
Official Full Name
coagulation factor IXprovided by VGNC
Primary source
VGNC:VGNC:1389
Locus tag
CK820_G0053420
See related
Ensembl:ENSPTRG00000022330
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) X NC_072421.2 (136995053..137028444)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) X NC_072421.1 (136991122..137024513)

Chromosome X - NC_072421.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129138601 Neighboring gene 3-oxo-5-alpha-steroid 4-dehydrogenase 1-like Neighboring gene MCF.2 cell line derived transforming sequence Neighboring gene small nucleolar RNA U13 Neighboring gene ATPase phospholipid transporting 11C Neighboring gene U6atac minor spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Comparison of DNA and protein polymorphisms between humans and chimpanzees. Satta Y. Genes Genet Syst, 2001 Jun. PMID 11569499

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in blood coagulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
coagulation factor IX
Names
christmas factor
coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B)
hemophilia B
NP_001129063.1
XP_016798133.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135591.1 → NP_001129063.1  coagulation factor IX precursor

    See identical proteins and their annotated locations for NP_001129063.1

    Status: PROVISIONAL

    Source sequence(s)
    AB062470
    UniProtKB/Swiss-Prot
    Q95ND7
    UniProtKB/TrEMBL
    A0A2J8IT47, H2R4I6
    Related
    ENSPTRP00000079315.1, ENSPTRT00000085797.1
    Conserved Domains (4) summary
    smart00069
    Location:28 → 92
    GLA; Domain containing Gla (gamma-carboxyglutamate) residues
    cd00054
    Location:93 → 129
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00190
    Location:227 → 457
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam14670
    Location:134 → 170
    FXa_inhibition; Coagulation Factor Xa inhibitory site

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072421.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    136995053..137028444
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016942644.2 → XP_016798133.1  coagulation factor IX isoform X1

    UniProtKB/TrEMBL
    H2R4I6
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95ND7.1 GenPept UniProtKB/Swiss-Prot:Q95ND7

Gene LinkOut

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