U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HDAC8 histone deacetylase 8 [ Pan troglodytes (chimpanzee) ]

Gene ID: 465712, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
HDAC8provided by VGNC
Official Full Name
histone deacetylase 8provided by VGNC
Primary source
VGNC:VGNC:111887
Locus tag
CK820_G0052754
See related
Ensembl:ENSPTRG00000051531
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: X
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) X NC_072421.2 (70129881..70375243, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) X NC_072421.1 (70125973..70371344, complement)

Chromosome X - NC_072421.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134809281 Neighboring gene ribosomal protein S4 X-linked Neighboring gene Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 Neighboring gene U2 spliceosomal RNA Neighboring gene phosphorylase kinase regulatory subunit alpha 1 Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
histone deacetylase 8

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072421.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    70129881..70375243 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016943141.3 → XP_016798630.1  histone deacetylase 8 isoform X4

    UniProtKB/TrEMBL
    A0A2I3T0A0, K7B694
    Related
    ENSPTRP00000092118.1
    Conserved Domains (1) summary
    cd10000
    Location:54 → 415
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_016943140.3 → XP_016798629.1  histone deacetylase 8 isoform X2

    UniProtKB/TrEMBL
    A0A2I3T0A0
    Conserved Domains (1) summary
    cd10000
    Location:54 → 409
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_054676559.2 → XP_054532534.1  histone deacetylase 8 isoform X11

  4. XM_016943147.3 → XP_016798636.1  histone deacetylase 8 isoform X13

    UniProtKB/TrEMBL
    A0A2I3TLJ7, K7B4I9
    Related
    ENSPTRP00000090110.1
    Conserved Domains (1) summary
    cl17011
    Location:54 → 324
    Arginase_HDAC; Arginase-like and histone-like hydrolases

  5. XM_054676558.2 → XP_054532533.1  histone deacetylase 8 isoform X7

  6. XM_016943139.3 → XP_016798628.1  histone deacetylase 8 isoform X1

    UniProtKB/TrEMBL
    A0A2I3T0A0

  7. XM_009439272.5 → XP_009437547.1  histone deacetylase 8 isoform X12

    Conserved Domains (1) summary
    cl17011
    Location:54 → 292
    Arginase_HDAC; Arginase-like and histone-like hydrolases

  8. XM_016943145.4 → XP_016798634.1  histone deacetylase 8 isoform X9

    UniProtKB/TrEMBL
    A0A2I3TLJ7

  9. XM_063803898.1 → XP_063659968.1  histone deacetylase 8 isoform X10

  10. XM_009439268.5 → XP_009437543.1  histone deacetylase 8 isoform X3

    UniProtKB/TrEMBL
    A0A2I3T0A0
    Conserved Domains (1) summary
    cd10000
    Location:54 → 383
    HDAC8; Histone deacetylase 8 (HDAC8)

  11. XM_016943142.4 → XP_016798631.1  histone deacetylase 8 isoform X5

    UniProtKB/TrEMBL
    A0A2I3T0A0

  12. XM_016943144.4 → XP_016798633.1  histone deacetylase 8 isoform X6

    UniProtKB/TrEMBL
    A0A2I3T0A0

  13. XM_024353156.3 → XP_024208924.1  histone deacetylase 8 isoform X8

    UniProtKB/TrEMBL
    A0A2I3T0A0
    Conserved Domains (1) summary
    cl17011
    Location:54 → 341
    Arginase_HDAC; Arginase-like and histone-like hydrolases

  14. XM_016943148.3 → XP_016798637.1  histone deacetylase 8 isoform X14

    UniProtKB/TrEMBL
    A0A2I3RPG2, A0A2J8IVY6, A0A6D2XIT7, K7BNN8
    Related
    ENSPTRP00000093713.1

  15. XM_016943149.3 → XP_016798638.1  histone deacetylase 8 isoform X17

  16. XM_054676560.2 → XP_054532535.1  histone deacetylase 8 isoform X15

  17. XM_003317520.4 → XP_003317568.1  histone deacetylase 8 isoform X16

    See identical proteins and their annotated locations for XP_003317568.1

    UniProtKB/TrEMBL
    K6ZI16
    Related
    ENSPTRP00000089865.1
    Conserved Domains (1) summary
    cl17011
    Location:54 → 185
    Arginase_HDAC; Arginase-like and histone-like hydrolases

RNA

  1. XR_001713995.3 RNA Sequence

  2. XR_010154640.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.