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JAK2 Janus kinase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 464979, updated on 11-Apr-2024

Summary

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Official Symbol
JAK2provided by VGNC
Official Full Name
Janus kinase 2provided by VGNC
Primary source
VGNC:VGNC:4770
Locus tag
CK820_G0023682
See related
Ensembl:ENSPTRG00000020744
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 11 NC_072409.2 (110770409..110921271, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 9 NC_072407.1 (7936440..8092558)

Chromosome 11 - NC_072409.2Genomic Context describing neighboring genes Neighboring gene relaxin 2 Neighboring gene insulin like 4 Neighboring gene insulin like 6 Neighboring gene transcription factor E2-alpha-like Neighboring gene MTRNR2L pseudogene Neighboring gene all trans-polyprenyl-diphosphate synthase PDSS1-like Neighboring gene casein kinase I-like Neighboring gene microRNA mir-101-2 Neighboring gene RNA terminal phosphate cyclase like 1 Neighboring gene small ribosomal subunit protein uS7-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth hormone receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase JAK2
Names
Janus kinase 2 (a protein tyrosine kinase)
XP_001139368.3
XP_016816044.2
XP_016816045.2
XP_016816046.2
XP_063644810.1
XP_063644811.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072409.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    110770409..110921271 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016960555.4 → XP_016816044.2  tyrosine-protein kinase JAK2 isoform X1

  2. XM_001139368.7 → XP_001139368.3  tyrosine-protein kinase JAK2 isoform X1

  3. XM_063788740.1 → XP_063644810.1  tyrosine-protein kinase JAK2 isoform X3

  4. XM_063788741.1 → XP_063644811.1  tyrosine-protein kinase JAK2 isoform X3

  5. XM_016960556.4 → XP_016816045.2  tyrosine-protein kinase JAK2 isoform X1

  6. XM_016960557.3 → XP_016816046.2  tyrosine-protein kinase JAK2 isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials
Miscellaneous