U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NOTCH1 notch receptor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 464865, updated on 29-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
NOTCH1provided by VGNC
Official Full Name
notch receptor 1provided by VGNC
Primary source
VGNC:VGNC:4807
Locus tag
CK820_G0012017
See related
Ensembl:ENSPTRG00000021561
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 9
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 11 NC_072409.2 (1894279..1946590)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 9 NC_072407.1 (116922121..116974432, complement)

Chromosome 11 - NC_072409.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112204409 Neighboring gene uncharacterized LOC107976825 Neighboring gene microRNA mir-126 Neighboring gene EGF like domain multiple 7 Neighboring gene uncharacterized protein C9orf163-like Neighboring gene SEC16 homolog A, endoplasmic reticulum export factor

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Notch binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of developmental process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
neurogenic locus notch homolog protein 1
Names
Notch homolog 1, translocation-associated
notch 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072409.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    1894279..1946590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_520371.7 → XP_520371.3  neurogenic locus notch homolog protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3S400, A0A2J8N9T5, A0A6D2XGF7, H2QY65
    Related
    ENSPTRP00000036924.6
    Conserved Domains (9) summary
    smart00004
    Location:1521 → 1561
    NL; Domain found in Notch and Lin-12
    cd00054
    Location:869 → 905
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00204
    Location:1922 → 2034
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:1880 → 1925
    ANK; ANK repeat [structural motif]
    pfam00066
    Location:1488 → 1522
    Notch; LNR domain
    pfam06816
    Location:1567 → 1618
    NOD; NOTCH protein
    pfam07684
    Location:1672 → 1729
    NODP; NOTCH protein
    pfam11936
    Location:2481 → 2540
    DUF3454; Domain of unknown function (DUF3454)
    pfam12796
    Location:1873 → 1958
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_009457720.5 → XP_009455995.1  neurogenic locus notch homolog protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3S400
    Related
    ENSPTRP00000071305.1
    Conserved Domains (11) summary
    smart00004
    Location:1404 → 1441
    NL; Domain found in Notch and Lin-12
    cd00054
    Location:831 → 867
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00204
    Location:1884 → 1996
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00008
    Location:1025 → 1055
    EGF; EGF-like domain
    pfam00066
    Location:1449 → 1484
    Notch; LNR domain
    pfam06816
    Location:1529 → 1580
    NOD; NOTCH protein
    pfam07684
    Location:1634 → 1691
    NODP; NOTCH protein
    pfam11235
    Location:2391 → 2476
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam11936
    Location:2441 → 2502
    DUF3454; Domain of unknown function (DUF3454)
    pfam12796
    Location:1894 → 1987
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:1842 → 1887
    ANK; ANK repeat [structural motif]

  3. XM_009457721.5 → XP_009455996.2  neurogenic locus notch homolog protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3S400

  4. XM_009457722.5 → XP_009455997.1  neurogenic locus notch homolog protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A2I3S400
    Related
    ENSPTRP00000082696.1
    Conserved Domains (11) summary
    smart00004
    Location:1366 → 1403
    NL; Domain found in Notch and Lin-12
    cd00054
    Location:793 → 829
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00204
    Location:1846 → 1958
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam00008
    Location:987 → 1017
    EGF; EGF-like domain
    pfam00066
    Location:1411 → 1446
    Notch; LNR domain
    pfam06816
    Location:1491 → 1542
    NOD; NOTCH protein
    pfam07684
    Location:1596 → 1653
    NODP; NOTCH protein
    pfam11235
    Location:2353 → 2438
    Med25_SD1; Mediator complex subunit 25 synapsin 1
    pfam11936
    Location:2403 → 2464
    DUF3454; Domain of unknown function (DUF3454)
    pfam12796
    Location:1856 → 1949
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:1804 → 1849
    ANK; ANK repeat [structural motif]

  5. XM_009457723.4 → XP_009455998.2  neurogenic locus notch homolog protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A2J8N9T8
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous