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RALGDS ral guanine nucleotide dissociation stimulator [ Pan troglodytes (chimpanzee) ]

Gene ID: 464824, updated on 3-Apr-2024

Summary

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Official Symbol
RALGDSprovided by VGNC
Official Full Name
ral guanine nucleotide dissociation stimulatorprovided by VGNC
Primary source
VGNC:VGNC:9195
Locus tag
CK820_G0012121
See related
Ensembl:ENSPTRG00000021509
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 11 NC_072409.2 (5312600..5363718)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 9 NC_072407.1 (113504994..113556143, complement)

Chromosome 11 - NC_072409.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807703 Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 Neighboring gene small nucleolar RNA U13 Neighboring gene bile salt-activated lipase-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ral guanine nucleotide dissociation stimulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072409.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    5312600..5363718
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003312365.6 → XP_003312413.1  ral guanine nucleotide dissociation stimulator isoform X4

    See identical proteins and their annotated locations for XP_003312413.1

    UniProtKB/TrEMBL
    A0A2I3TBI0, A0A2J8NAE6, A0A6D2XEI0, K6ZA96
    Related
    ENSPTRP00000085077.1
    Conserved Domains (4) summary
    smart00229
    Location:57 → 193
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd00155
    Location:327 → 589
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd17209
    Location:743 → 828
    RA_RalGDS; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator (RalGDS) and similar proteins
    pfam15685
    Location:178 → 303
    GGN; Gametogenetin

  2. XM_054659239.2 → XP_054515214.1  ral guanine nucleotide dissociation stimulator isoform X1

  3. XM_054659240.2 → XP_054515215.1  ral guanine nucleotide dissociation stimulator isoform X2

  4. XM_054659241.2 → XP_054515216.1  ral guanine nucleotide dissociation stimulator isoform X3

  5. XM_054659243.2 → XP_054515218.1  ral guanine nucleotide dissociation stimulator isoform X8

  6. XM_054659244.2 → XP_054515219.1  ral guanine nucleotide dissociation stimulator isoform X12

  7. XM_063787474.1 → XP_063643544.1  ral guanine nucleotide dissociation stimulator isoform X13

  8. XM_054659242.2 → XP_054515217.1  ral guanine nucleotide dissociation stimulator isoform X6

  9. XM_063787473.1 → XP_063643543.1  ral guanine nucleotide dissociation stimulator isoform X9

  10. XM_003312367.6 → XP_003312415.1  ral guanine nucleotide dissociation stimulator isoform X15

    UniProtKB/TrEMBL
    A0A2I3TBI0, A0A2I3TXQ2, A0A2J8NAG1, A0A6D2WH02
    Related
    ENSPTRP00000093877.1
    Conserved Domains (4) summary
    smart00229
    Location:95 → 219
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    PHA03247
    Location:276 → 341
    PHA03247; large tegument protein UL36; Provisional
    cd00155
    Location:353 → 615
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd17209
    Location:769 → 854
    RA_RalGDS; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator (RalGDS) and similar proteins

  11. XM_016961965.4 → XP_016817454.2  ral guanine nucleotide dissociation stimulator isoform X14

  12. XM_016961962.4 → XP_016817451.1  ral guanine nucleotide dissociation stimulator isoform X11

    UniProtKB/TrEMBL
    A0A2J8NAH0, A0A2J8NAH4
    Conserved Domains (4) summary
    smart00229
    Location:112 → 236
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    PHA03247
    Location:293 → 358
    PHA03247; large tegument protein UL36; Provisional
    cd00155
    Location:370 → 632
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd17209
    Location:786 → 871
    RA_RalGDS; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator (RalGDS) and similar proteins

  13. XM_016961958.4 → XP_016817447.1  ral guanine nucleotide dissociation stimulator isoform X5

  14. XM_016961959.4 → XP_016817448.1  ral guanine nucleotide dissociation stimulator isoform X7

  15. XM_016961961.4 → XP_016817450.1  ral guanine nucleotide dissociation stimulator isoform X10

    UniProtKB/TrEMBL
    A0A2I3SZ06, A0A2J8NAE7, A0A6D2WZA1, H2QY37, K7ANV8
    Related
    ENSPTRP00000036808.3
    Conserved Domains (4) summary
    smart00229
    Location:112 → 248
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    PHA03247
    Location:305 → 370
    PHA03247; large tegument protein UL36; Provisional
    cd00155
    Location:382 → 644
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd17209
    Location:798 → 883
    RA_RalGDS; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator (RalGDS) and similar proteins
Nucleotide Protein
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