PTGES2 prostaglandin E synthase 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PTGES2provided by VGNC
Official Full Name: prostaglandin E synthase 2provided by VGNC
Primary source: VGNC:VGNC:4837
Locus tag: CK820_G0012272
See related: Ensembl:ENSPTRG00000021411 Ensembl:ENSPTRG00000048759
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	11	NC_072409.2 (10325927..10332981)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	9	NC_072407.1 (108535743..108542789, complement)

Chromosome 11 - NC_072409.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-147521 (e-PCR)
- UniSTS:172822

RH68883 (e-PCR)
- UniSTS:26663

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables prostaglandin-E synthase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prostaglandin E synthase 2

NP_001233456.1

EC 5.3.99.3

XP_063643228.1

EC 5.3.99.3

XP_063643229.1

EC 5.3.99.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001246527.1 → NP_001233456.1 prostaglandin E synthase 2

See identical proteins and their annotated locations for NP_001233456.1

Status: PROVISIONAL

Source sequence(s)

AK307043

UniProtKB/TrEMBL

A0A2I3T900, A0A2J8NBI3, A0A6D2YB78, G2HJX9

Related

ENSPTRP00000085716.1, ENSPTRT00000101167.1

Conserved Domains (2) summary

cd03197
Location:224 → 370

GST_C_mPGES2; C-terminal, alpha helical domain of microsomal Prostaglandin E synthase Type 2

cd03040
Location:101 → 177

GST_N_mPGES2; GST_N family; microsomal Prostaglandin E synthase Type 2 (mPGES2) subfamily; mPGES2 is a membrane-anchored dimeric protein containing a CXXC motif which catalyzes the isomerization of PGH2 to PGE2. Unlike cytosolic PGE synthase (cPGES) and microsomal ...