U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SH2D3C SH2 domain containing 3C [ Pan troglodytes (chimpanzee) ]

Gene ID: 464753, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
SH2D3Cprovided by VGNC
Official Full Name
SH2 domain containing 3Cprovided by VGNC
Primary source
VGNC:VGNC:4862
Locus tag
CK820_G0012296
See related
Ensembl:ENSPTRG00000021397
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 9
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 11 NC_072409.2 (10677240..10720622)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 9 NC_072407.1 (108148102..108191442, complement)

Chromosome 11 - NC_072409.2Genomic Context describing neighboring genes Neighboring gene endoglin Neighboring gene uncharacterized LOC107976777 Neighboring gene folylpolyglutamate synthase Neighboring gene cyclin dependent kinase 9 Neighboring gene torsin family 2 member A Neighboring gene tetratricopeptide repeat domain 16 Neighboring gene cilia and flagella associated protein 157 Neighboring gene peptidyl-tRNA hydrolase 1 homolog

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
SH2 domain-containing protein 3C

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072409.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    10677240..10720622
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001150131.6 → XP_001150131.1  SH2 domain-containing protein 3C isoform X3

    UniProtKB/TrEMBL
    A0A2I3RD51, A0A2J8NBL7, A0A6D2WYY5, H2QXX7
    Related
    ENSPTRP00000036571.5
    Conserved Domains (3) summary
    cd10337
    Location:213 → 347
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    COG3921
    Location:57 → 174
    COG3921; Uncharacterized conserved protein [Function unknown]
    cl02485
    Location:585 → 754
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  2. XM_016961717.4 → XP_016817206.1  SH2 domain-containing protein 3C isoform X6

  3. XM_009457333.5 → XP_009455608.1  SH2 domain-containing protein 3C isoform X1

    Conserved Domains (2) summary
    cd10337
    Location:213 → 347
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:585 → 776
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  4. XM_009457334.5 → XP_009455609.1  SH2 domain-containing protein 3C isoform X2

    Conserved Domains (2) summary
    cd10337
    Location:213 → 347
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:585 → 775
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  5. XM_009457335.5 → XP_009455610.1  SH2 domain-containing protein 3C isoform X9

    Conserved Domains (2) summary
    cd10337
    Location:213 → 347
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:585 → 699
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  6. XM_063788227.1 → XP_063644297.1  SH2 domain-containing protein 3C isoform X12

  7. XM_063788228.1 → XP_063644298.1  SH2 domain-containing protein 3C isoform X17

    UniProtKB/TrEMBL
    A0A2I3SLT1, A0A2J8NBM7, A0A6D2W0R7

  8. XM_016961718.4 → XP_016817207.1  SH2 domain-containing protein 3C isoform X7

    UniProtKB/TrEMBL
    A0A2I3RD51

  9. XM_063788226.1 → XP_063644296.1  SH2 domain-containing protein 3C isoform X8

  10. XM_001150074.7 → XP_001150074.1  SH2 domain-containing protein 3C isoform X16

    UniProtKB/TrEMBL
    A0A2I3RD51, A0A2I3REM6, A0A2J8NBK8, A0A6D2XCD6
    Related
    ENSPTRP00000062842.1
    Conserved Domains (2) summary
    cd10337
    Location:56 → 190
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:428 → 597
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  11. XM_054659114.1 → XP_054515089.1  SH2 domain-containing protein 3C isoform X14

  12. XM_009457337.5 → XP_009455612.1  SH2 domain-containing protein 3C isoform X13

    UniProtKB/TrEMBL
    A0A2I3RD51
    Conserved Domains (2) summary
    cd10337
    Location:56 → 190
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:428 → 619
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  13. XM_063788229.1 → XP_063644299.1  SH2 domain-containing protein 3C isoform X17

    UniProtKB/TrEMBL
    A0A2I3SLT1, A0A2J8NBM7, A0A6D2W0R7

  14. XM_016961715.4 → XP_016817204.1  SH2 domain-containing protein 3C isoform X4

    UniProtKB/TrEMBL
    A0A2I3RD51

  15. XM_016961716.4 → XP_016817205.1  SH2 domain-containing protein 3C isoform X5

    UniProtKB/TrEMBL
    A0A2I3RD51

  16. XM_520275.8 → XP_520275.2  SH2 domain-containing protein 3C isoform X10

    UniProtKB/TrEMBL
    A0A2I3RD51, A0A2I3SNG9, A0A2J8NBL1, A0A6D2XLC1
    Related
    ENSPTRP00000078552.1
    Conserved Domains (2) summary
    cd10337
    Location:55 → 189
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:427 → 596
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  17. XM_009457336.5 → XP_009455611.1  SH2 domain-containing protein 3C isoform X11

    UniProtKB/TrEMBL
    A0A2I3RD51, A0A2J8NBN6
    Related
    ENSPTRP00000062567.1
    Conserved Domains (2) summary
    cd10337
    Location:53 → 187
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:425 → 594
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  18. XM_016961719.3 → XP_016817208.1  SH2 domain-containing protein 3C isoform X15

    UniProtKB/TrEMBL
    A0A2I3RD51
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.