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ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 464399, updated on 3-Apr-2024

Summary

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Official Symbol
ASAP1provided by VGNC
Official Full Name
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1provided by VGNC
Primary source
VGNC:VGNC:2459
Locus tag
CK820_G0039262
See related
Ensembl:ENSPTRG00000020587
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
DDEF1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 7 NC_072405.2 (140304483..140696419, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 8 NC_072406.1 (144903515..145298461, complement)

Chromosome 7 - NC_072405.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134810919 Neighboring gene CYFIP related Rac1 interactor B Neighboring gene U7 small nuclear RNA Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA12 Neighboring gene uncharacterized LOC134810921 Neighboring gene uncharacterized LOC134810920 Neighboring gene uncharacterized LOC107976445 Neighboring gene adenylate cyclase 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cilium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of membrane tubulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in podosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Names
development and differentiation enhancing factor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    140304483..140696419 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063817373.1 → XP_063673443.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X9

  2. XM_054657023.2 → XP_054512998.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X7

  3. XM_009455915.5 → XP_009454190.2  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A2I3TGH6, A0A2J8KF69, A0A6D2WKI7, H2QWQ5, K7D7X0
    Related
    ENSPTRP00000035200.5
    Conserved Domains (7) summary
    cd07641
    Location:54 → 268
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:1071 → 1127
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:601 → 689
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:316 → 422
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:601 → 634
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:439 → 555
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:724 → 1060
    Atrophin-1; Atrophin-1 family

  4. XM_009455918.5 → XP_009454193.2  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A2I3S0H8, A0A2I3TGH6
    Related
    ENSPTRP00000070494.1

  5. XM_054657022.2 → XP_054512997.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X5

  6. XM_024345277.3 → XP_024201045.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A2I3TGH6
    Conserved Domains (7) summary
    cd11965
    Location:1082 → 1138
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:612 → 700
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:327 → 433
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:612 → 645
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:450 → 566
    ArfGap; Putative GTPase activating protein for Arf
    cl12013
    Location:73 → 279
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    cl26464
    Location:735 → 1071
    Atrophin-1; Atrophin-1 family

  7. XM_016959864.4 → XP_016815353.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3TGH6, A0A2I3TKP4, A0A2J8KF70, A0A6D2Y706
    Related
    ENSPTRP00000089797.1
    Conserved Domains (7) summary
    cd07641
    Location:47 → 261
    BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
    cd11965
    Location:1064 → 1120
    SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
    cd00204
    Location:594 → 682
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13251
    Location:309 → 415
    PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
    sd00045
    Location:594 → 627
    ANK; ANK repeat [structural motif]
    pfam01412
    Location:432 → 548
    ArfGap; Putative GTPase activating protein for Arf
    cl26464
    Location:717 → 1053
    Atrophin-1; Atrophin-1 family

  8. XM_063817372.1 → XP_063673442.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X8

  9. XM_063817369.1 → XP_063673439.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X2

  10. XM_063817370.1 → XP_063673440.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3TKP4, A0A2J8KF70, A0A6D2Y706

  11. XM_063817371.1 → XP_063673441.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A2I3TKP4, A0A2J8KF70, A0A6D2Y706

  12. XM_063817375.1 → XP_063673445.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

  13. XM_054657026.1 → XP_054513001.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

Nucleotide Protein
Heading Accession and Version

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