RIPK2 receptor interacting serine/threonine kinase 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: RIPK2provided by VGNC
Official Full Name: receptor interacting serine/threonine kinase 2provided by VGNC
Primary source: VGNC:VGNC:14578
Locus tag: CK820_G0001779
See related: Ensembl:ENSPTRG00000020405
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 8

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	7	NC_072405.2 (100015993..100049680)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	8	NC_072406.1 (104599754..104632326)

Chromosome 7 - NC_072405.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH48506 (e-PCR)
- UniSTS:2139

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables JUN kinase kinase kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in innate immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of apoptotic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: receptor-interacting serine/threonine-protein kinase 2

XP_016815139.1

EC 2.7.11.1

XP_054513366.1

EC 2.7.11.1

XP_519850.2

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

100015993..100049680

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_519850.7 → XP_519850.2 receptor-interacting serine/threonine-protein kinase 2 isoform X1

See identical proteins and their annotated locations for XP_519850.2

UniProtKB/TrEMBL

A0A2I3RYC1, A0A2J8PLE6, A0A6D2X2C1, H2QWE5

Related

ENSPTRP00000034905.2

Conserved Domains (2) summary

cd08786
Location:437 → 523

CARD_RIP2_CARD3; Caspase activation and recruitment domain of Receptor Interacting Protein 2

cd14026
Location:20 → 303

STKc_RIP2; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 2
XM_054657391.2 → XP_054513366.1 receptor-interacting serine/threonine-protein kinase 2 isoform X3
XM_016959650.3 → XP_016815139.1 receptor-interacting serine/threonine-protein kinase 2 isoform X2

UniProtKB/TrEMBL

A0A2I3RYC1