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HEY1 hes related family bHLH transcription factor with YRPW motif 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 464248, updated on 29-Mar-2024

Summary

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Official Symbol
HEY1provided by VGNC
Official Full Name
hes related family bHLH transcription factor with YRPW motif 1provided by VGNC
Primary source
VGNC:VGNC:8180
Locus tag
CK820_G0022383
See related
Ensembl:ENSPTRG00000020364
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 7 NC_072405.2 (88407488..88411543, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 8 NC_072406.1 (93435767..93439685, complement)

Chromosome 7 - NC_072405.2Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL3-like Neighboring gene stathmin 2 Neighboring gene uncharacterized LOC748710 Neighboring gene U7 small nuclear RNA Neighboring gene uncharacterized LOC104007655

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in circulatory system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hairy/enhancer-of-split related with YRPW motif protein 1
Names
hairy/enhancer-of-split related with YRPW motif 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    88407488..88411543 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_519823.8 → XP_519823.2  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2

    See identical proteins and their annotated locations for XP_519823.2

    UniProtKB/TrEMBL
    A0A2I3TMB5, A0A2J8M9W7, A0A6D2VXH8, K7D7U5
    Related
    ENSPTRP00000069126.1
    Conserved Domains (2) summary
    smart00511
    Location:120 → 166
    ORANGE; Orange domain
    cl00081
    Location:41 → 122
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  2. XM_009455539.5 → XP_009453814.1  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1

    See identical proteins and their annotated locations for XP_009453814.1

    UniProtKB/TrEMBL
    A0A2I3TMB5, A0A2J8M9W8
    Conserved Domains (2) summary
    smart00511
    Location:124 → 170
    ORANGE; Orange domain
    cl00081
    Location:41 → 126
    bHLH_SF; basic Helix Loop Helix (bHLH) domain superfamily

  3. XM_009455540.5 → XP_009453815.1  hairy/enhancer-of-split related with YRPW motif protein 1 isoform X3

    UniProtKB/TrEMBL
    H2QWB8
    Related
    ENSPTRP00000034843.4
    Conserved Domains (1) summary
    smart00511
    Location:30 → 76
    ORANGE; Orange domain
Nucleotide Protein
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