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NCOA2 nuclear receptor coactivator 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 464226, updated on 3-Apr-2024

Summary

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Official Symbol
NCOA2provided by VGNC
Official Full Name
nuclear receptor coactivator 2provided by VGNC
Primary source
VGNC:VGNC:835
Locus tag
CK820_G0022262
See related
Ensembl:ENSPTRG00000020333
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 7 NC_072405.2 (78745220..79042310, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 8 NC_072406.1 (83762607..84059683, complement)

Chromosome 7 - NC_072405.2Genomic Context describing neighboring genes Neighboring gene PR/SET domain 14 Neighboring gene histone H2A.Z-like Neighboring gene transcription factor BTF3-like Neighboring gene small ribosomal subunit protein uS13-like Neighboring gene uncharacterized LOC104007640

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hormone stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nuclear receptor coactivator 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    78745220..79042310 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054656809.2 → XP_054512784.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43

  2. XM_063817157.1 → XP_063673227.1  nuclear receptor coactivator 2 isoform X1

  3. XM_063817184.1 → XP_063673254.1  nuclear receptor coactivator 2 isoform X5

  4. XM_063817181.1 → XP_063673251.1  nuclear receptor coactivator 2 isoform X4

  5. XM_063817177.1 → XP_063673247.1  nuclear receptor coactivator 2 isoform X3

  6. XM_063817174.1 → XP_063673244.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43

  7. XM_063817165.1 → XP_063673235.1  nuclear receptor coactivator 2 isoform X1

  8. XM_063817169.1 → XP_063673239.1  nuclear receptor coactivator 2 isoform X1

  9. XM_063817172.1 → XP_063673242.1  nuclear receptor coactivator 2 isoform X1

  10. XM_063817182.1 → XP_063673252.1  nuclear receptor coactivator 2 isoform X5

  11. XM_063817178.1 → XP_063673248.1  nuclear receptor coactivator 2 isoform X4

  12. XM_016959559.3 → XP_016815048.1  nuclear receptor coactivator 2 isoform X3

    UniProtKB/TrEMBL
    H2QWA2
    Conserved Domains (9) summary
    smart00353
    Location:35 → 88
    HLH; helix loop helix domain
    cd00130
    Location:123 → 213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:119 → 215
    PAS; PAS fold
    pfam07469
    Location:1212 → 1269
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:1002 → 1047
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:640 → 709
    SRC-1; Steroid receptor coactivator
    pfam14598
    Location:268 → 378
    PAS_11; PAS domain
    pfam16279
    Location:731 → 816
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:463 → 587
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein

  13. XM_016959550.4 → XP_016815039.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43, H2QWA2
    Conserved Domains (10) summary
    smart00353
    Location:35 → 88
    HLH; helix loop helix domain
    cd00130
    Location:123 → 213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:1281 → 1338
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:1071 → 1116
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:640 → 709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:892 → 1372
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:268 → 378
    PAS_11; PAS domain
    pfam16279
    Location:731 → 816
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:463 → 587
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
    cl26950
    Location:1269 → 1399
    LsmAD; LsmAD domain

  14. XM_063817155.1 → XP_063673225.1  nuclear receptor coactivator 2 isoform X1

  15. XM_063817163.1 → XP_063673233.1  nuclear receptor coactivator 2 isoform X1

  16. XM_063817161.1 → XP_063673231.1  nuclear receptor coactivator 2 isoform X1

  17. XM_063817162.1 → XP_063673232.1  nuclear receptor coactivator 2 isoform X1

  18. XM_016959551.4 → XP_016815040.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43, H2QWA2
    Conserved Domains (10) summary
    smart00353
    Location:35 → 88
    HLH; helix loop helix domain
    cd00130
    Location:123 → 213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:1281 → 1338
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:1071 → 1116
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:640 → 709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:892 → 1372
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:268 → 378
    PAS_11; PAS domain
    pfam16279
    Location:731 → 816
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:463 → 587
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
    cl26950
    Location:1269 → 1399
    LsmAD; LsmAD domain

  19. XM_063817175.1 → XP_063673245.1  nuclear receptor coactivator 2 isoform X3

  20. XM_063817156.1 → XP_063673226.1  nuclear receptor coactivator 2 isoform X1

  21. XM_063817179.1 → XP_063673249.1  nuclear receptor coactivator 2 isoform X4

  22. XM_054656812.2 → XP_054512787.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43

  23. XM_063817164.1 → XP_063673234.1  nuclear receptor coactivator 2 isoform X1

  24. XM_063817167.1 → XP_063673237.1  nuclear receptor coactivator 2 isoform X1

  25. XM_063817183.1 → XP_063673253.1  nuclear receptor coactivator 2 isoform X5

  26. XM_016959560.3 → XP_016815049.1  nuclear receptor coactivator 2 isoform X3

    UniProtKB/TrEMBL
    H2QWA2
    Conserved Domains (9) summary
    smart00353
    Location:35 → 88
    HLH; helix loop helix domain
    cd00130
    Location:123 → 213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam00989
    Location:119 → 215
    PAS; PAS fold
    pfam07469
    Location:1212 → 1269
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:1002 → 1047
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:640 → 709
    SRC-1; Steroid receptor coactivator
    pfam14598
    Location:268 → 378
    PAS_11; PAS domain
    pfam16279
    Location:731 → 816
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:463 → 587
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein

  27. XM_063817158.1 → XP_063673228.1  nuclear receptor coactivator 2 isoform X1

  28. XM_063817166.1 → XP_063673236.1  nuclear receptor coactivator 2 isoform X1

  29. XM_063817176.1 → XP_063673246.1  nuclear receptor coactivator 2 isoform X3

  30. XM_054656810.2 → XP_054512785.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43

  31. XM_063817159.1 → XP_063673229.1  nuclear receptor coactivator 2 isoform X1

  32. XM_063817168.1 → XP_063673238.1  nuclear receptor coactivator 2 isoform X1

  33. XM_063817160.1 → XP_063673230.1  nuclear receptor coactivator 2 isoform X1

  34. XM_063817173.1 → XP_063673243.1  nuclear receptor coactivator 2 isoform X1

  35. XM_016959557.4 → XP_016815046.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43, H2QWA2
    Related
    ENSPTRP00000069925.1
    Conserved Domains (10) summary
    smart00353
    Location:35 → 88
    HLH; helix loop helix domain
    cd00130
    Location:123 → 213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:1281 → 1338
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:1071 → 1116
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:640 → 709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:892 → 1372
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:268 → 378
    PAS_11; PAS domain
    pfam16279
    Location:731 → 816
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:463 → 587
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
    cl26950
    Location:1269 → 1399
    LsmAD; LsmAD domain

  36. XM_063817170.1 → XP_063673240.1  nuclear receptor coactivator 2 isoform X1

  37. XM_016959556.4 → XP_016815045.1  nuclear receptor coactivator 2 isoform X2

    UniProtKB/TrEMBL
    A0A2I3RZ80, A0A2J8M9L5, A0A6D2XX43, H2QWA2
    Conserved Domains (10) summary
    smart00353
    Location:35 → 88
    HLH; helix loop helix domain
    cd00130
    Location:123 → 213
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam07469
    Location:1281 → 1338
    DUF1518; Domain of unknown function (DUF1518)
    pfam08815
    Location:1071 → 1116
    Nuc_rec_co-act; Nuclear receptor coactivator
    pfam08832
    Location:640 → 709
    SRC-1; Steroid receptor coactivator
    pfam09606
    Location:892 → 1372
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam14598
    Location:268 → 378
    PAS_11; PAS domain
    pfam16279
    Location:731 → 816
    DUF4927; Domain of unknown function (DUF4927)
    pfam16665
    Location:463 → 587
    NCOA_u2; Unstructured region on nuclear receptor coactivator protein
    cl26950
    Location:1269 → 1399
    LsmAD; LsmAD domain

  38. XM_063817171.1 → XP_063673241.1  nuclear receptor coactivator 2 isoform X1

Nucleotide Protein
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