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CYP7A1 cytochrome P450 family 7 subfamily A member 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 464191, updated on 29-Mar-2024

Summary

Official Symbol
CYP7A1provided by VGNC
Official Full Name
cytochrome P450 family 7 subfamily A member 1provided by VGNC
Primary source
VGNC:VGNC:6563
Locus tag
CK820_G0038802
See related
Ensembl:ENSPTRG00000020275
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 8
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 7 NC_072405.2 (67112937..67122934, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 8 NC_072406.1 (72122883..72132878, complement)

Chromosome 7 - NC_072405.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107976499 Neighboring gene tyrosine-protein phosphatase non-receptor type 11-like Neighboring gene UBX domain protein 2B Neighboring gene syndecan binding protein Neighboring gene small ribosomal subunit protein eS26-like Neighboring gene neutral sphingomyelinase activation associated factor

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cholesterol 7-alpha-monooxygenase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cholesterol catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cholesterol 7-alpha-monooxygenase; cytochrome P450 7A1
Names
cytochrome P450, family 7, subfamily A, polypeptide 1
XP_519773.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072405.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    67112937..67122934 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_519773.5XP_519773.2  cytochrome P450 7A1

    UniProtKB/TrEMBL
    A0A2J8KHI6, A0A6D2X891, H2QW73
    Related
    ENSPTRP00000034711.2
    Conserved Domains (1) summary
    pfam00067
    Location:32497
    p450; Cytochrome P450