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CHRM2 cholinergic receptor muscarinic 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 463758, updated on 29-Mar-2024

Summary

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Official Symbol
CHRM2provided by VGNC
Official Full Name
cholinergic receptor muscarinic 2provided by VGNC
Primary source
VGNC:VGNC:4306
Locus tag
CK820_G0013902
See related
Ensembl:ENSPTRG00000050632
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (152229672..152384031)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (146302094..146456512)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene 26S proteasome regulatory subunit 4-like Neighboring gene small nucleolar RNA U13 Neighboring gene microRNA mir-490 Neighboring gene uncharacterized LOC129135446 Neighboring gene large ribosomal subunit protein eL18-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Human-specific amino acid changes found in 103 protein-coding genes. Kitano T, et al. Mol Biol Evol, 2004 May. PMID 15014171

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled acetylcholine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of heart contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of smooth muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
muscarinic acetylcholine receptor M2
Names
Muscarinic acetylcholine receptor M2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    152229672..152384031
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001147545.7 → XP_001147545.1  muscarinic acetylcholine receptor M2

    See identical proteins and their annotated locations for XP_001147545.1

    UniProtKB/Swiss-Prot
    Q9N2A7
    UniProtKB/TrEMBL
    A0A2J8QTN5, A0A6D2WSM4, H2RAP9
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_009454280.5 → XP_009452555.1  muscarinic acetylcholine receptor M2

    See identical proteins and their annotated locations for XP_009452555.1

    UniProtKB/Swiss-Prot
    Q9N2A7
    UniProtKB/TrEMBL
    A0A2J8QTN5, A0A6D2WSM4, H2RAP9
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_001147469.7 → XP_001147469.1  muscarinic acetylcholine receptor M2

    See identical proteins and their annotated locations for XP_001147469.1

    UniProtKB/Swiss-Prot
    Q9N2A7
    UniProtKB/TrEMBL
    A0A2J8QTN5, A0A6D2WSM4, H2RAP9
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_001147308.5 → XP_001147308.1  muscarinic acetylcholine receptor M2

    See identical proteins and their annotated locations for XP_001147308.1

    UniProtKB/Swiss-Prot
    Q9N2A7
    UniProtKB/TrEMBL
    A0A2J8QTN5, A0A6D2WSM4, H2RAP9
    Conserved Domains (1) summary
    cd15297
    Location:24 → 451
    7tmA_mAChR_M2; muscarinic acetylcholine receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_008536274.2 RNA Sequence

  2. XR_008536273.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9N2A7.1 GenPept UniProtKB/Swiss-Prot:Q9N2A7

Gene LinkOut

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