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SMO smoothened, frizzled class receptor [ Pan troglodytes (chimpanzee) ]

Gene ID: 463718, updated on 3-Apr-2024

Summary

Official Symbol
SMOprovided by VGNC
Official Full Name
smoothened, frizzled class receptorprovided by VGNC
Primary source
VGNC:VGNC:4508
Locus tag
CK820_G0013769
See related
Ensembl:ENSPTRG00000019680 Ensembl:ENSPTRG00000047167
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (144542821..144567717)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (138615003..138639913)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene dual specificity mitogen-activated protein kinase kinase 2-like Neighboring gene tetraspanin 33 Neighboring gene adenosylhomocysteinase like 2 Neighboring gene hyaluronan synthase 2-like Neighboring gene U7 small nuclear RNA

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables patched binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in commissural neuron axon guidance IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in pattern specification process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in smoothened signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cilium IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
smoothened homolog; protein smoothened
Names
smoothened, frizzled family receptor
smoothened, seven transmembrane spanning receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    144542821..144567717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016945374.4XP_016800863.3  protein smoothened isoform X1

    UniProtKB/TrEMBL
    H2QVC7
  2. XM_024358040.3XP_024213808.2  protein smoothened isoform X2

RNA

  1. XR_010158991.1 RNA Sequence