U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GRB10 growth factor receptor bound protein 10 [ Pan troglodytes (chimpanzee) ]

Gene ID: 463410, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
GRB10provided by VGNC
Official Full Name
growth factor receptor bound protein 10provided by VGNC
Primary source
VGNC:VGNC:4380
Locus tag
CK820_G0031402
See related
Ensembl:ENSPTRG00000019191
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 7
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 6 NC_072404.2 (56417990..56621416, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 7 NC_072405.1 (54063572..54266998, complement)

Chromosome 6 - NC_072404.2Genomic Context describing neighboring genes Neighboring gene fidgetin like 1 Neighboring gene dopa decarboxylase Neighboring gene uncharacterized LOC129144558 Neighboring gene large ribosomal subunit protein eL39-like Neighboring gene small nucleolar RNA SNORA4

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables insulin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
growth factor receptor-bound protein 10

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    56417990..56621416 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024357835.3 → XP_024213603.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2I3TN24, A0A2J8L8X9, A0A6D2WC34
    Conserved Domains (4) summary
    cd10415
    Location:429 → 536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228 → 350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108 → 199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368 → 409
    BPS; BPS (Between PH and SH2)

  2. XM_054687546.2 → XP_054543521.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  3. XM_063815394.1 → XP_063671464.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  4. XM_009453073.5 → XP_009451348.1  growth factor receptor-bound protein 10 isoform X4

    See identical proteins and their annotated locations for XP_009451348.1

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2I3TN24, A0A2J8L8X9, A0A6D2WC34
    Conserved Domains (4) summary
    cd10415
    Location:429 → 536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228 → 350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108 → 199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368 → 409
    BPS; BPS (Between PH and SH2)

  5. XM_009453065.5 → XP_009451340.2  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TN24, A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7
    Related
    ENSPTRP00000090638.1
    Conserved Domains (4) summary
    cd01787
    Location:166 → 248
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:487 → 594
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:286 → 408
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:426 → 467
    BPS; BPS (Between PH and SH2)

  6. XM_024357836.3 → XP_024213604.1  growth factor receptor-bound protein 10 isoform X5

    UniProtKB/TrEMBL
    A0A2J8L8X7
    Conserved Domains (4) summary
    cd01787
    Location:204 → 286
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:525 → 632
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:324 → 446
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:464 → 505
    BPS; BPS (Between PH and SH2)

  7. XM_054687536.2 → XP_054543511.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  8. XM_024357834.3 → XP_024213602.1  growth factor receptor-bound protein 10 isoform X1

    UniProtKB/TrEMBL
    A0A2J8L8X7
    Conserved Domains (4) summary
    cd01787
    Location:215 → 297
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:536 → 643
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:335 → 457
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:475 → 516
    BPS; BPS (Between PH and SH2)

  9. XM_063815387.1 → XP_063671457.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  10. XM_063815381.1 → XP_063671451.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  11. XM_063815386.1 → XP_063671456.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  12. XM_063815383.1 → XP_063671453.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  13. XM_054687542.2 → XP_054543517.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  14. XM_063815390.1 → XP_063671460.1  growth factor receptor-bound protein 10 isoform X3

    UniProtKB/TrEMBL
    A0A2I3THJ7, A0A2J8L8X6, A0A6D2WIZ5

  15. XM_063815395.1 → XP_063671465.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  16. XM_054687539.2 → XP_054543514.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  17. XM_063815389.1 → XP_063671459.1  growth factor receptor-bound protein 10 isoform X3

    UniProtKB/TrEMBL
    A0A2I3THJ7, A0A2J8L8X6, A0A6D2WIZ5

  18. XM_063815401.1 → XP_063671471.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  19. XM_063815393.1 → XP_063671463.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  20. XM_063815384.1 → XP_063671454.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  21. XM_063815380.1 → XP_063671450.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  22. XM_063815399.1 → XP_063671469.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  23. XM_063815379.1 → XP_063671449.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  24. XM_063815392.1 → XP_063671462.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  25. XM_063815385.1 → XP_063671455.1  growth factor receptor-bound protein 10 isoform X2

    UniProtKB/TrEMBL
    A0A2J8L8Y4, A0A6D2WD33, H2RDR9, K7BFT7

  26. XM_063815397.1 → XP_063671467.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  27. XM_063815398.1 → XP_063671468.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  28. XM_063815391.1 → XP_063671461.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  29. XM_063815388.1 → XP_063671458.1  growth factor receptor-bound protein 10 isoform X3

    UniProtKB/TrEMBL
    A0A2I3THJ7, A0A2J8L8X6, A0A6D2WIZ5

  30. XM_016957478.4 → XP_016812967.1  growth factor receptor-bound protein 10 isoform X3

    UniProtKB/TrEMBL
    A0A2I3THJ7, A0A2I3TN24, A0A2J8L8X6, A0A6D2WIZ5
    Related
    ENSPTRP00000088741.1
    Conserved Domains (4) summary
    cd01787
    Location:160 → 242
    GRB7_RA; RA (RAS-associated like) domain of Grb7
    cd10415
    Location:481 → 588
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:280 → 402
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    pfam08947
    Location:420 → 461
    BPS; BPS (Between PH and SH2)

  31. XM_016957480.4 → XP_016812969.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2I3TN24, A0A2J8L8X9, A0A6D2WC34
    Conserved Domains (4) summary
    cd10415
    Location:429 → 536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228 → 350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108 → 199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368 → 409
    BPS; BPS (Between PH and SH2)

  32. XM_054687540.2 → XP_054543515.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  33. XM_063815400.1 → XP_063671470.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2J8L8X9, A0A6D2WC34

  34. XM_016957479.4 → XP_016812968.1  growth factor receptor-bound protein 10 isoform X4

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2I3TN24, A0A2J8L8X9, A0A6D2WC34
    Conserved Domains (4) summary
    cd10415
    Location:429 → 536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228 → 350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108 → 199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368 → 409
    BPS; BPS (Between PH and SH2)

  35. XM_009453069.5 → XP_009451344.1  growth factor receptor-bound protein 10 isoform X4

    See identical proteins and their annotated locations for XP_009451344.1

    UniProtKB/TrEMBL
    A0A2I3SXR3, A0A2I3TN24, A0A2J8L8X9, A0A6D2WC34
    Conserved Domains (4) summary
    cd10415
    Location:429 → 536
    SH2_Grb10; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 10 (Grb10) proteins
    cd01259
    Location:228 → 350
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16141
    Location:108 → 199
    RA_GRB10; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 10
    pfam08947
    Location:368 → 409
    BPS; BPS (Between PH and SH2)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.