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PLG plasminogen [ Pan troglodytes (chimpanzee) ]

Gene ID: 463117, updated on 29-Mar-2024

Summary

Official Symbol
PLGprovided by VGNC
Official Full Name
plasminogenprovided by VGNC
Primary source
VGNC:VGNC:11165
Locus tag
CK820_G0042761
See related
Ensembl:ENSPTRG00000018774
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
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Genomic context

Location:
chromosome: 6
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 5 NC_072403.2 (172803375..172854825)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 6 NC_072404.1 (172801868..172853318)

Chromosome 5 - NC_072403.2Genomic Context describing neighboring genes Neighboring gene apolipoprotein(a)-like Neighboring gene uncharacterized LOC134810388 Neighboring gene lipoprotein(a) Neighboring gene uncharacterized LOC134810389 Neighboring gene mitogen-activated protein kinase kinase kinase 4

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
plasminogen
XP_024213265.1
XP_024213267.1
XP_024213268.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    172803375..172854825
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024357497.2XP_024213265.1  plasminogen isoform X1

    UniProtKB/TrEMBL
    A0A2J8JZZ2, H2QU06
    Conserved Domains (3) summary
    smart00130
    Location:101183
    KR; Kringle domain
    cd00190
    Location:581804
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cd01099
    Location:3897
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
  2. XM_024357499.2XP_024213267.1  plasminogen isoform X2

    UniProtKB/TrEMBL
    H2QU06
    Conserved Domains (3) summary
    smart00130
    Location:101183
    KR; Kringle domain
    cd00190
    Location:581779
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    cd01099
    Location:3897
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...
  3. XM_024357500.2XP_024213268.1  plasminogen isoform X3

    Conserved Domains (3) summary
    smart00130
    Location:183263
    KR; Kringle domain
    cd00108
    Location:102182
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd01099
    Location:3897
    PAN_AP_HGF; Subfamily of PAN/APPLE-like domains; present in N-terminal (N) domains of plasminogen/hepatocyte growth factor proteins, and various proteins found in Bilateria, such as leech anti-platelet proteins. PAN/APPLE domains fulfill diverse biological functions ...