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ESR1 estrogen receptor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 463079, updated on 29-Mar-2024

Summary

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Official Symbol
ESR1provided by VGNC
Official Full Name
estrogen receptor 1provided by VGNC
Primary source
VGNC:VGNC:2781
Locus tag
CK820_G0037884
See related
Ensembl:ENSPTRG00000018716
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 5 NC_072403.2 (163617888..164065753)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 6 NC_072404.1 (163616367..164061914)

Chromosome 5 - NC_072403.2Genomic Context describing neighboring genes Neighboring gene required for meiotic nuclear division 1 homolog Neighboring gene acidic residue methyltransferase 1 Neighboring gene coiled-coil domain containing 170 Neighboring gene U6 spliceosomal RNA Neighboring gene spectrin repeat containing nuclear envelope protein 1 Neighboring gene Nanog homeobox pseudogene 11 Neighboring gene uncharacterized LOC129144341

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estrogen response element binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear estrogen receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to estrogen stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular estrogen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of chromatin IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
estrogen receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    163617888..164065753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054686430.2 → XP_054542405.1  estrogen receptor isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q9X9, A0A6D2W6V3, H2QTX3

  2. XM_003311549.5 → XP_003311597.1  estrogen receptor isoform X2

    See identical proteins and their annotated locations for XP_003311597.1

    UniProtKB/TrEMBL
    A0A2J8Q9X9, A0A6D2W6V3, H2QTX3
    Conserved Domains (4) summary
    cd06949
    Location:310 → 547
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:180 → 261
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:42 → 181
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:552 → 595
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal

  3. XM_054686432.2 → XP_054542407.1  estrogen receptor isoform X4

  4. XM_009452244.4 → XP_009450519.1  estrogen receptor isoform X1

    See identical proteins and their annotated locations for XP_009450519.1

    Conserved Domains (4) summary
    cd06949
    Location:312 → 549
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:180 → 263
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:42 → 181
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:554 → 597
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal

  5. XM_054686431.2 → XP_054542406.1  estrogen receptor isoform X3

  6. XM_063813580.1 → XP_063669650.1  estrogen receptor isoform X1

  7. XM_009452245.4 → XP_009450520.1  estrogen receptor isoform X1

    See identical proteins and their annotated locations for XP_009450520.1

    Conserved Domains (4) summary
    cd06949
    Location:312 → 549
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:180 → 263
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:42 → 181
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:554 → 597
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal

  8. XM_003311548.5 → XP_003311596.1  estrogen receptor isoform X2

    See identical proteins and their annotated locations for XP_003311596.1

    UniProtKB/TrEMBL
    A0A2J8Q9X9, A0A6D2W6V3, H2QTX3
    Related
    ENSPTRP00000031932.2
    Conserved Domains (4) summary
    cd06949
    Location:310 → 547
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:180 → 261
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam02159
    Location:42 → 181
    Oest_recep; Oestrogen receptor
    pfam12743
    Location:552 → 595
    ESR1_C; Oestrogen-type nuclear receptor final C-terminal
Nucleotide Protein
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