HDAC2 histone deacetylase 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: HDAC2provided by VGNC
Official Full Name: histone deacetylase 2provided by VGNC
Primary source: VGNC:VGNC:11094
Locus tag: CK820_G0000476
See related: Ensembl:ENSPTRG00000018519
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	5	NC_072403.2 (125839660..125870633, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	6	NC_072404.1 (125838145..125869036, complement)

Chromosome 5 - NC_072403.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D8S2279 (e-PCR)
- UniSTS:473907

D11S3430 (e-PCR)
- UniSTS:152671

D10S16 (e-PCR)
- UniSTS:155756

D1S1423 (e-PCR)
- UniSTS:149619

D11S3114 (e-PCR)
- UniSTS:152207

G42073 (e-PCR)
- UniSTS:93134

STS-N62138 (e-PCR)
- UniSTS:64478

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables histone deacetylase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of NuRD complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: histone deacetylase 2

XP_024213143.1

EC 3.5.1.98

XP_063669434.1

EC 3.5.1.98

XP_518700.2

EC 3.5.1.98

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

125839660..125870633 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_518700.6 → XP_518700.2 histone deacetylase 2 isoform X1

UniProtKB/TrEMBL

A0A2I3RQ94, H2R700

Related

ENSPTRP00000049696.3

Conserved Domains (3) summary

cd10011
Location:102 → 467

HDAC2; Histone deacetylase 2 (HDAC2)

PTZ00063
Location:102 → 491

PTZ00063; histone deacetylase; Provisional

pfam14797
Location:486 → 580

SEEEED; Serine-rich region of AP3B1, clathrin-adaptor complex
XM_024357375.3 → XP_024213143.1 histone deacetylase 2 isoform X2

UniProtKB/TrEMBL

A0A2I3SRY3, A0A2J8PU26

Conserved Domains (3) summary

pfam05285
Location:362 → 438

SDA1

pfam18004
Location:406 → 458

RPN2_C; 26S proteasome regulatory subunit RPN2 C-terminal domain

cl17011
Location:1 → 344

Arginase_HDAC; Arginase-like and histone-like hydrolases
XM_063813364.1 → XP_063669434.1 histone deacetylase 2 isoform X2

UniProtKB/TrEMBL

A0A2J8PU26