RIPK1 receptor interacting serine/threonine kinase 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: RIPK1provided by VGNC
Official Full Name: receptor interacting serine/threonine kinase 1provided by VGNC
Primary source: VGNC:VGNC:11209
Locus tag: CK820_G0017321
See related: Ensembl:ENSPTRG00000017672
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	5	NC_072403.2 (9015365..9066213)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	6	NC_072404.1 (9015412..9066215)

Chromosome 5 - NC_072403.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH46743 (e-PCR)
- UniSTS:56476

WI-14042 (e-PCR)
- UniSTS:30656

D6S1199E (e-PCR)
- UniSTS:34000

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: receptor-interacting serine/threonine-protein kinase 1

Names: receptor (TNFRSF)-interacting serine-threonine kinase 1

XP_001160973.3

EC 2.7.11.1

XP_016810314.1

EC 2.7.11.1

XP_016810315.1

EC 2.7.11.1

XP_054541549.1

EC 2.7.11.1

XP_054541550.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072403.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

9015365..9066213

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016954825.4 → XP_016810314.1 receptor-interacting serine/threonine-protein kinase 1 isoform X2

UniProtKB/TrEMBL

A0A2J8MU17, A0A6D2XTQ2, H2QS79

Conserved Domains (2) summary

cd08777
Location:583 → 668

Death_RIP1; Death Domain of Receptor-Interacting Protein 1

cd14027
Location:23 → 290

STKc_RIP1; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 1
XM_016954826.4 → XP_016810315.1 receptor-interacting serine/threonine-protein kinase 1 isoform X2

UniProtKB/TrEMBL

A0A2J8MU17, A0A6D2XTQ2, H2QS79

Conserved Domains (2) summary

cd08777
Location:583 → 668

Death_RIP1; Death Domain of Receptor-Interacting Protein 1

cd14027
Location:23 → 290

STKc_RIP1; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 1
XM_054685574.2 → XP_054541549.1 receptor-interacting serine/threonine-protein kinase 1 isoform X2

UniProtKB/TrEMBL

A0A2J8MU17, A0A6D2XTQ2, H2QS79
XM_001160973.6 → XP_001160973.3 receptor-interacting serine/threonine-protein kinase 1 isoform X1

Conserved Domains (2) summary

cd08777
Location:753 → 838

Death_RIP1; Death Domain of Receptor-Interacting Protein 1

cd14027
Location:193 → 460

STKc_RIP1; Catalytic domain of the Serine/Threonine kinase, Receptor Interacting Protein 1
XM_054685575.1 → XP_054541550.1 receptor-interacting serine/threonine-protein kinase 1 isoform X3