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HTR4 5-hydroxytryptamine receptor 4 [ Pan troglodytes (chimpanzee) ]

Gene ID: 462175, updated on 29-Mar-2024

Summary

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Official Symbol
HTR4provided by VGNC
Official Full Name
5-hydroxytryptamine receptor 4provided by VGNC
Primary source
VGNC:VGNC:13511
Locus tag
CK820_G0010041
See related
Ensembl:ENSPTRG00000017389
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 4 NC_072402.2 (146176400..146386644, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 5 NC_072403.1 (146188817..146398982, complement)

Chromosome 4 - NC_072402.2Genomic Context describing neighboring genes Neighboring gene serine peptidase inhibitor Kazal type 9 Neighboring gene F-box protein 38 Neighboring gene uncharacterized LOC129144028 Neighboring gene adrenoceptor beta 2 Neighboring gene SH3 domain and tetratricopeptide repeats 2 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of appetite IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-hydroxytryptamine receptor 4
Names
5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
serotonin 5-HT4 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    146176400..146386644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016954012.4 → XP_016809501.1  5-hydroxytryptamine receptor 4 isoform X2

    UniProtKB/TrEMBL
    A0A2I3T0F1, A0A2J8NJA0, A0A2J8NJB5, A0A6D2YAQ0, A0A6D2YBI3, H2R334
    Related
    ENSPTRP00000061733.1
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_001162339.8 → XP_001162339.1  5-hydroxytryptamine receptor 4 isoform X1

    See identical proteins and their annotated locations for XP_001162339.1

    UniProtKB/TrEMBL
    A0A2I3S0Q5, A0A2J8NJA7, A0A2J8NJB5, A0A6D2WNR4, A0A6D2YAQ0, H2R334
    Related
    ENSPTRP00000070527.1
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  3. XM_001162258.7 → XP_001162258.1  5-hydroxytryptamine receptor 4 isoform X4

    See identical proteins and their annotated locations for XP_001162258.1

    UniProtKB/TrEMBL
    A0A2I3TWI0, A0A2J8NJA4, A0A2J8NJB5, A0A6D2YAQ0, A0A6D2YCJ5, H2R334
    Related
    ENSPTRP00000093596.1
    Conserved Domains (1) summary
    cd15056
    Location:20 → 323
    7tmA_5-HT4; serotonin receptor subtype 4, member of the class A family of seven-transmembrane G protein-coupled receptors

  4. XM_063811579.1 → XP_063667649.1  5-hydroxytryptamine receptor 4 isoform X3

RNA

  1. XR_010157366.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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