PRLR prolactin receptor [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PRLRprovided by VGNC
Official Full Name: prolactin receptorprovided by VGNC
Primary source: VGNC:VGNC:13568
Locus tag: CK820_G0044897
See related: Ensembl:ENSPTRG00000016787
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (77560385..77741328)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (77748146..77922203)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

human.PRLR (e-PCR)
- UniSTS:181773

STS-M31661 (e-PCR)
- UniSTS:28174

D5S2592 (e-PCR)
- UniSTS:29994

RH16173 (e-PCR)
- UniSTS:13650

RH46591 (e-PCR)
- UniSTS:90728

RH102042 (e-PCR)
- UniSTS:96376

D5S1900 (e-PCR)
- UniSTS:181710

STS-W35369 (e-PCR)
- UniSTS:51923

D5S1900 (e-PCR)
- UniSTS:44788

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cytokine binding	IEA Inferred from Electronic Annotation more info	PubMed
enables peptide hormone binding	IEA Inferred from Electronic Annotation more info	PubMed
enables prolactin receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cytokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of receptor complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prolactin receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

77560385..77741328

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001150064.8 → XP_001150064.2 prolactin receptor isoform X1

See identical proteins and their annotated locations for XP_001150064.2

UniProtKB/TrEMBL

A0A2J8JSG6, A0A6D2XPN4, H2QQR5

Related

ENSPTRP00000028787.4

Conserved Domains (3) summary

cd00063
Location:127 → 225

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam12772
Location:286 → 362

GHBP; Growth hormone receptor binding

cl21522
Location:24 → 120

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
XM_063811324.1 → XP_063667394.1 prolactin receptor isoform X2

UniProtKB/TrEMBL

A0A2I3RRC9, A0A2J8JSH6, A0A6D2XNE8
XM_063811323.1 → XP_063667393.1 prolactin receptor isoform X1

UniProtKB/TrEMBL

A0A2J8JSG6, A0A6D2XPN4, H2QQR5
XM_016953442.4 → XP_016808931.1 prolactin receptor isoform X1

UniProtKB/TrEMBL

A0A2J8JSG6, A0A6D2XPN4, H2QQR5

Conserved Domains (3) summary

cd00063
Location:127 → 225

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam12772
Location:286 → 362

GHBP; Growth hormone receptor binding

cl21522
Location:24 → 120

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...