ITGA1 integrin subunit alpha 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: ITGA1provided by VGNC
Official Full Name: integrin subunit alpha 1provided by VGNC
Primary source: VGNC:VGNC:4053
Locus tag: CK820_G0040528
See related: Ensembl:ENSPTRG00000016859
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: PELO
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (61704616..61877939, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (62133205..62306503, complement)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH123048 (e-PCR)
- UniSTS:135441

D5S1686E (e-PCR)
- UniSTS:151074

RH120591 (e-PCR)
- UniSTS:132424

L28346 (e-PCR)
- UniSTS:65354

RH64941 (e-PCR)
- UniSTS:33355

SGC33636 (e-PCR)
- UniSTS:64870

SHGC-155766 (e-PCR)
- UniSTS:184182

WI-17921 (e-PCR)
- UniSTS:39813

SHGC-32850 (e-PCR)
- UniSTS:30854

Pelo (e-PCR), detects polymorphism
- UniSTS:243340

RH121270 (e-PCR)
- UniSTS:138381

PMC310876P1 (e-PCR)
- UniSTS:272785

SHGC-53304 (e-PCR)
- UniSTS:75937

PELO (e-PCR)
- UniSTS:505762

RH64850 (e-PCR)
- UniSTS:85942

ITGA1_2521 (e-PCR)
- UniSTS:280789

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables integrin binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell adhesion mediated by integrin	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-cell adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell-matrix adhesion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in integrin-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in external side of plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
part_of integrin complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: integrin alpha-1

Names: integrin, alpha 1; pelota homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

61704616..61877939 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_517769.9 → XP_517769.2 integrin alpha-1

See identical proteins and their annotated locations for XP_517769.2

UniProtKB/TrEMBL

A0A2J8K912, A0A6D2X7V1, H2QQV4

Related

ENSPTRP00000028883.3

Conserved Domains (3) summary

smart00191
Location:568 → 621

Int_alpha; Integrin alpha (beta-propellor repeats)

cd01469
Location:171 → 351

vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...

pfam08441
Location:664 → 1033

Integrin_alpha2; Integrin alpha