LOC461830 general transcription factor IIH subunit 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Gene symbol: LOC461830
Gene description: general transcription factor IIH subunit 2
Locus tag: CK820_G0034212
See related: Ensembl:ENSPTRG00000016953
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: GTF2H2; GTF2H2C; GTF2H2D
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Genomic context

Location:: chromosome: 4

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (45063604..45096148, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (45478070..45511108, complement)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D5S1661E (e-PCR)
- UniSTS:151049

A007J09 (e-PCR)
- UniSTS:61966

G17015 (e-PCR)
- UniSTS:528

D15S1477 (e-PCR)
- UniSTS:474482

D5S1833 (e-PCR)
- UniSTS:82551

GTF2H2_3374 (e-PCR)
- UniSTS:471455

D11S4687 (e-PCR)
- UniSTS:81068

SHGC-58588 (e-PCR)
- UniSTS:94409

RH45971 (e-PCR)
- UniSTS:31718

D5S1609E (e-PCR)
- UniSTS:151030

Homology

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in nucleotide-excision repair	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of transcription factor TFIIH core complex	IEA Inferred from Electronic Annotation more info	PubMed
part_of transcription factor TFIIH holo complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: general transcription factor IIH subunit 2

Names: GTF2H2 family member C; general transcription factor IIH, polypeptide 2, 44kDa; general transcription factor IIH, polypeptide 2C; general transcription factor IIH, polypeptide 2D

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

45063604..45096148 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054685063.2 → XP_054541038.1 general transcription factor IIH subunit 2

UniProtKB/TrEMBL

A0A2J8L0V9, A0A6D2WHX1, H2QR13
XM_001158018.8 → XP_001158018.1 general transcription factor IIH subunit 2

See identical proteins and their annotated locations for XP_001158018.1

UniProtKB/TrEMBL

A0A2I3TD59, A0A2J8L0V9, A0A6D2WHX1, H2QR13

Conserved Domains (2) summary

COG5151
Location:11 → 385

SSL1; RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1 [Transcription / DNA replication, recombination, and repair]

cd01453
Location:56 → 236

vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
XM_001158068.6 → XP_001158068.1 general transcription factor IIH subunit 2

See identical proteins and their annotated locations for XP_001158068.1

UniProtKB/TrEMBL

A0A2I3TD59, A0A2J8L0V9, A0A6D2WHX1, H2QR13

Related

ENSPTRP00000087185.1

Conserved Domains (2) summary

COG5151
Location:11 → 385

SSL1; RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1 [Transcription / DNA replication, recombination, and repair]

cd01453
Location:56 → 236

vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
XM_001158128.8 → XP_001158128.1 general transcription factor IIH subunit 2

See identical proteins and their annotated locations for XP_001158128.1

UniProtKB/TrEMBL

A0A2I3TD59, A0A2J8L0V9, A0A6D2WHX1, H2QR13

Related

ENSPTRP00000029040.5

Conserved Domains (2) summary

COG5151
Location:11 → 385

SSL1; RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH, subunit SSL1 [Transcription / DNA replication, recombination, and repair]

cd01453
Location:56 → 236

vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
XM_054685061.2 → XP_054541036.1 general transcription factor IIH subunit 2

UniProtKB/TrEMBL

A0A2J8L0V9, A0A6D2WHX1, H2QR13