RASA1 RAS p21 protein activator 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: RASA1provided by VGNC
Official Full Name: RAS p21 protein activator 1provided by VGNC
Primary source: VGNC:VGNC:7143
Locus tag: CK820_G0009242
See related: Ensembl:ENSPTRG00000017062
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 25

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	4	NC_072402.2 (28759666..28884428, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	5	NC_072403.1 (29182382..29306365, complement)

Chromosome 4 - NC_072402.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH69991 (e-PCR)
- UniSTS:30743

RH69527 (e-PCR)
- UniSTS:18467

RH15818 (e-PCR)
- UniSTS:82227

RH104298 (e-PCR)
- UniSTS:98623

SGC30189 (e-PCR)
- UniSTS:64329

STS-M23379 (e-PCR)
- UniSTS:79697

RH93053 (e-PCR)
- UniSTS:87644

RH69245 (e-PCR)
- UniSTS:81773

RASA1 (e-PCR)
- UniSTS:504952

1578 (e-PCR)
- UniSTS:46983

WI-14548 (e-PCR)
- UniSTS:28554

RH45809 (e-PCR)
- UniSTS:12171

D5S2372 (e-PCR)
- UniSTS:48013

RASA1_8586 (e-PCR)
- UniSTS:467854

RH78240 (e-PCR)
- UniSTS:18319

STS-N22145 (e-PCR)
- UniSTS:53956

STS-AA004311 (e-PCR)
- UniSTS:43473

RH103694 (e-PCR)
- UniSTS:98019

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ras GTPase-activating protein 1

Names: RAS p21 protein activator (GTPase activating protein) 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072402.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

28759666..28884428 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063811113.1 → XP_063667183.1 ras GTPase-activating protein 1 isoform X4
XM_063811111.1 → XP_063667181.1 ras GTPase-activating protein 1 isoform X2
XM_063811114.1 → XP_063667184.1 ras GTPase-activating protein 1 isoform X6
XM_517663.8 → XP_517663.3 ras GTPase-activating protein 1 isoform X1

See identical proteins and their annotated locations for XP_517663.3

UniProtKB/TrEMBL

A0A2J8NMU6, A0A6D2WFK1, H2QR74, K7BAI1

Related

ENSPTRP00000029205.4

Conserved Domains (6) summary

cd08400
Location:591 → 716

C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)

cd10353
Location:161 → 264

SH2_Nterm_RasGAP; N-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)

cd10354
Location:350 → 426

SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)

cd11788
Location:281 → 339

SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1

cd05391
Location:714 → 1045

RasGAP_p120GAP; Ras-GTPase Activating Domain of p120

cd13260
Location:489 → 576

PH_RASA1; RAS p21 protein activator (GTPase activating protein) 1 Pleckstrin homology (PH) domain
XM_063811112.1 → XP_063667182.1 ras GTPase-activating protein 1 isoform X3
XM_001145642.6 → XP_001145642.1 ras GTPase-activating protein 1 isoform X5

See identical proteins and their annotated locations for XP_001145642.1

UniProtKB/TrEMBL

A0A2J8NMX5, K7DQJ8

Related

ENSPTRP00000074903.1

Conserved Domains (6) summary

cd08400
Location:414 → 539

C2_Ras_p21A1; C2 domain present in RAS p21 protein activator 1 (RasA1)

cd10354
Location:173 → 249

SH2_Cterm_RasGAP; C-terminal Src homology 2 (SH2) domain found in Ras GTPase-activating protein 1 (GAP)

cd11788
Location:104 → 162

SH3_RasGAP; Src Homology 3 domain of Ras GTPase-Activating Protein 1

cd05391
Location:537 → 868

RasGAP_p120GAP; Ras-GTPase Activating Domain of p120

cl15255
Location:4 → 87

SH2; Src homology 2 (SH2) domain

cl17171
Location:312 → 399

PH-like; Pleckstrin homology-like domain