PPP3CA protein phosphatase 3 catalytic subunit alpha [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PPP3CAprovided by VGNC
Official Full Name: protein phosphatase 3 catalytic subunit alphaprovided by VGNC
Primary source: VGNC:VGNC:7727
Locus tag: CK820_G0022224
See related: Ensembl:ENSPTRG00000016315
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (102486403..102809418, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (102486384..102810067, complement)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

PPP3CA (e-PCR)
- UniSTS:519172

SHGC-50332 (e-PCR)
- UniSTS:82707

SHGC-67753 (e-PCR)
- UniSTS:65299

SHGC-19097 (e-PCR)
- UniSTS:82708

G66787 (e-PCR)
- UniSTS:166694

SHGC4-996 (e-PCR)
- UniSTS:54320

D4S1591 (e-PCR)
- UniSTS:54321

G62618 (e-PCR)
- UniSTS:139598

WI-18743 (e-PCR)
- UniSTS:50264

G59661 (e-PCR)
- UniSTS:136815

EST26A4-T (e-PCR)
- UniSTS:263284

SHGC-106455 (e-PCR)
- UniSTS:169860

SHGC-106093 (e-PCR)
- UniSTS:169622

PPP3CA (e-PCR)
- UniSTS:503449

WI-16419 (e-PCR)
- UniSTS:61859

SHGC-67693 (e-PCR)
- UniSTS:30634

WI-20975 (e-PCR)
- UniSTS:30635

J05479 (e-PCR)
- UniSTS:124858

SHGC-67255 (e-PCR)
- UniSTS:14011

RH66646 (e-PCR)
- UniSTS:56514

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calmodulin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calmodulin-dependent protein phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in calcineurin-NFAT signaling cascade	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of calcineurin complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform; protein phosphatase 3 catalytic subunit alpha

Names: protein phosphatase 3, catalytic subunit, alpha isozyme

XP_016807409.1

EC 3.1.3.16

XP_016807410.1

EC 3.1.3.16

XP_054539202.1

EC 3.1.3.16

XP_063665779.1

EC 3.1.3.16

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

102486403..102809418 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016951921.4 → XP_016807410.1 protein phosphatase 3 catalytic subunit alpha isoform X2

UniProtKB/TrEMBL

A0A2I3RWU9, A0A2J8MAX0, A0A8I3B2A8, K7AI04, K7ALG6

Related

ENSPTRP00000082977.1

Conserved Domains (1) summary

cd07416
Location:41 → 345

MPP_PP2B; PP2B, metallophosphatase domain
XM_016951920.4 → XP_016807409.1 protein phosphatase 3 catalytic subunit alpha isoform X1

UniProtKB/TrEMBL

A0A2I3RSP9, A0A2I3RWU9, A0A2J8MAV4, A0A6D2X3S7

Related

ENSPTRP00000067730.1

Conserved Domains (1) summary

cd07416
Location:41 → 345

MPP_PP2B; PP2B, metallophosphatase domain
XM_054683227.2 → XP_054539202.1 protein phosphatase 3 catalytic subunit alpha isoform X4
XM_063809709.1 → XP_063665779.1 protein phosphatase 3 catalytic subunit alpha isoform X3