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SNCA synuclein alpha [ Pan troglodytes (chimpanzee) ]

Gene ID: 461375, updated on 13-Apr-2024

Summary

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Official Symbol
SNCAprovided by VGNC
Official Full Name
synuclein alphaprovided by VGNC
Primary source
VGNC:VGNC:1998
Locus tag
CK820_G0022124
See related
Ensembl:ENSPTRG00000052247
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 3 NC_072401.2 (91094093..91208396, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 4 NC_072402.1 (91094064..91208369, complement)

Chromosome 3 - NC_072401.2Genomic Context describing neighboring genes Neighboring gene GPRIN family member 3 Neighboring gene uncharacterized LOC129143745 Neighboring gene multimerin 1 Neighboring gene coiled-coil serine rich protein 1 Neighboring gene thymosin beta-4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. alpha-Synuclein A53T substitution associated with Parkinson disease also marks the divergence of Old World and New World primates. Hamilton BA. Genomics, 2004 Apr. PMID 15028296

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cuprous ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dopamine secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic vesicle endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-synuclein
Names
synuclein, alpha (non A4 component of amyloid precursor)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009158.4 → NP_001009158.1  alpha-synuclein

    See identical proteins and their annotated locations for NP_001009158.1

    Status: VALIDATED

    Source sequence(s)
    JAQQLN020000003
    UniProtKB/Swiss-Prot
    P61145
    UniProtKB/TrEMBL
    A0A2J8MAD9, K7AKQ9
    Related
    ENSPTRP00000090843.1, ENSPTRT00000110874.1
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    91094093..91208396 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009447912.5 → XP_009446187.1  alpha-synuclein isoform X1

    See identical proteins and their annotated locations for XP_009446187.1

    UniProtKB/Swiss-Prot
    P61145
    UniProtKB/TrEMBL
    A0A2J8MAD9, K7AKQ9
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  2. XM_009447911.5 → XP_009446186.1  alpha-synuclein isoform X1

    See identical proteins and their annotated locations for XP_009446186.1

    UniProtKB/Swiss-Prot
    P61145
    UniProtKB/TrEMBL
    A0A2J8MAD9, K7AKQ9
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein

  3. XM_063808077.1 → XP_063664147.1  alpha-synuclein isoform X1

    UniProtKB/Swiss-Prot
    P61145
    UniProtKB/TrEMBL
    A0A2J8MAD9

  4. XM_009447913.5 → XP_009446188.1  alpha-synuclein isoform X1

    See identical proteins and their annotated locations for XP_009446188.1

    UniProtKB/Swiss-Prot
    P61145
    UniProtKB/TrEMBL
    A0A2J8MAD9, K7AKQ9
    Conserved Domains (1) summary
    pfam01387
    Location:1 → 131
    Synuclein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P61145.1 GenPept UniProtKB/Swiss-Prot:P61145

Gene LinkOut

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