RBPJ recombination signal binding protein for immunoglobulin kappa J region [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: RBPJprovided by VGNC
Official Full Name: recombination signal binding protein for immunoglobulin kappa J regionprovided by VGNC
Primary source: VGNC:VGNC:675
Locus tag: CK820_G0007571
See related: Ensembl:ENSPTRG00000015968
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as: RBPSUH
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	3	NC_072401.2 (26784288..26899912)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	4	NC_072402.1 (26785207..26899893)

Chromosome 3 - NC_072401.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

SHGC-67732 (e-PCR)
- UniSTS:80649

D4S858 (e-PCR)
- UniSTS:57921

G48208 (e-PCR)
- UniSTS:95305

Rbpsuh-rs3 (e-PCR), detects polymorphism
- UniSTS:166228

STS-T67414 (e-PCR)
- UniSTS:82298

SHGC-67733 (e-PCR)
- UniSTS:43905

D4S863 (e-PCR)
- UniSTS:59532

SHGC-64083 (e-PCR)
- UniSTS:928

SHGC-59198 (e-PCR)
- UniSTS:49588

B355YA5 (e-PCR)
- UniSTS:80325

RBPSUH_4000 (e-PCR)
- UniSTS:463309

SHGC-67311 (e-PCR)
- UniSTS:84976

NoName (e-PCR)
- UniSTS:480496

SHGC-59196 (e-PCR)
- UniSTS:66553

SHGC-133079 (e-PCR)
- UniSTS:171005

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Notch signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of MAML1-RBP-Jkappa- ICN1 complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: recombining binding protein suppressor of hairless

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072401.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

26784288..26899912

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001166354.7 → XP_001166354.2 recombining binding protein suppressor of hairless isoform X1
XM_054682815.2 → XP_054538790.1 recombining binding protein suppressor of hairless isoform X3

UniProtKB/TrEMBL

A0A2I3TAJ2, A0A2J8NVV9, A0A6D2XS89
XM_517135.8 → XP_517135.2 recombining binding protein suppressor of hairless isoform X2

See identical proteins and their annotated locations for XP_517135.2

UniProtKB/TrEMBL

A0A2I3TEY3, A0A2J8NVV2

Related

ENSPTRP00000087417.1

Conserved Domains (3) summary

cd01176
Location:337 → 433

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:193 → 315

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:35 → 160

LAG1-DNAbind; LAG1, DNA binding
XM_063809444.1 → XP_063665514.1 recombining binding protein suppressor of hairless isoform X3

UniProtKB/TrEMBL

A0A2I3TAJ2, A0A2J8NVV9, A0A6D2XS89
XM_054682816.2 → XP_054538791.1 recombining binding protein suppressor of hairless isoform X3

UniProtKB/TrEMBL

A0A2I3TAJ2, A0A2J8NVV9, A0A6D2XS89
XM_054682817.1 → XP_054538792.1 recombining binding protein suppressor of hairless isoform X4

UniProtKB/TrEMBL

A0A2J8NVW6
XM_001166553.6 → XP_001166553.1 recombining binding protein suppressor of hairless isoform X3

See identical proteins and their annotated locations for XP_001166553.1

UniProtKB/TrEMBL

A0A2I3TAJ2, A0A2I3TEY3, A0A2J8NVV9, A0A6D2XS89

Related

ENSPTRP00000086257.1

Conserved Domains (3) summary

cd01176
Location:336 → 432

IPT_RBP-Jkappa; IPT domain of the recombination signal Jkappa binding protein (RBP-Jkappa). RBP-J kappa, was initially considered to be involved in V(D)J recombination because of its DNA binding specificity and structural similarity to site-specific recombinases known ...

pfam09270
Location:192 → 314

BTD; Beta-trefoil DNA-binding domain

pfam09271
Location:34 → 159

LAG1-DNAbind; LAG1, DNA binding