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HES1 hes family bHLH transcription factor 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 460942, updated on 29-Mar-2024

Summary

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Official Symbol
HES1provided by VGNC
Official Full Name
hes family bHLH transcription factor 1provided by VGNC
Primary source
VGNC:VGNC:1835
Locus tag
CK820_G0023534
See related
Ensembl:ENSPTRG00000045020
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (197319828..197322338)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (197229229..197231716)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134807017 Neighboring gene uncharacterized LOC107970879 Neighboring gene uncharacterized LOC100615125 Neighboring gene carboxypeptidase N subunit 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables E-box binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables N-box binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor HES-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    197319828..197322338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_516956.7 → XP_516956.1  transcription factor HES-1

    See identical proteins and their annotated locations for XP_516956.1

    UniProtKB/TrEMBL
    A0A2J8M6D3, A0A6D2YBA9, H2QNZ9, K7D4K7
    Related
    ENSPTRP00000064171.1
    Conserved Domains (2) summary
    cd11459
    Location:33 → 95
    bHLH-O_HES1_4; basic helix-loop-helix-orange (bHLH-O) domain found in hairy and enhancer of split HES-1, HES-4 and similar proteins
    pfam07527
    Location:110 → 148
    Hairy_orange; Hairy Orange
Nucleotide Protein
Heading Accession and Version

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