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ATR ATR serine/threonine kinase [ Pan troglodytes (chimpanzee) ]

Gene ID: 460745, updated on 3-Apr-2024

Summary

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Official Symbol
ATRprovided by VGNC
Official Full Name
ATR serine/threonine kinaseprovided by VGNC
Primary source
VGNC:VGNC:6166
Locus tag
CK820_G0006473
See related
Ensembl:ENSPTRG00000015483
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
48
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (145660129..145789930, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (145569501..145699430, complement)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene 5'-3' exoribonuclease 1 Neighboring gene U6 spliceosomal RNA Neighboring gene U1 spliceosomal RNA Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 1-like Neighboring gene plastin 1 Neighboring gene transient receptor potential cation channel subfamily C member 1 Neighboring gene U7 small nuclear RNA Neighboring gene large ribosomal subunit protein uL2-like Neighboring gene procollagen C-endopeptidase enhancer 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase ATR
Names
ataxia telangiectasia and Rad3 related protein
XP_016797579.1
XP_024211505.1
XP_054537089.1
XP_063662360.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    145660129..145789930 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054681114.2 → XP_054537089.1  serine/threonine-protein kinase ATR isoform X4

  2. XM_063806290.1 → XP_063662360.1  serine/threonine-protein kinase ATR isoform X2

  3. XM_016942090.3 → XP_016797579.1  serine/threonine-protein kinase ATR isoform X1

    UniProtKB/TrEMBL
    A0A2J8P361, A0A6D2XSN7, H2R801, K7BXR2, K7DR10
    Related
    ENSPTRP00000051017.4
    Conserved Domains (4) summary
    smart00802
    Location:1119 → 1224
    UME; Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
    COG5032
    Location:2133 → 2644
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd00892
    Location:2293 → 2567
    PIKKc_ATR; Catalytic domain of Ataxia telangiectasia and Rad3-related proteins
    pfam02259
    Location:1771 → 2092
    FAT; FAT domain

  4. XM_024355737.3 → XP_024211505.1  serine/threonine-protein kinase ATR isoform X3

    UniProtKB/TrEMBL
    K7BXR2
    Conserved Domains (4) summary
    smart00802
    Location:1055 → 1160
    UME; Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
    COG5032
    Location:2069 → 2580
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd00892
    Location:2229 → 2503
    PIKKc_ATR; Catalytic domain of Ataxia telangiectasia and Rad3-related proteins
    pfam02259
    Location:1707 → 2028
    FAT; FAT domain

RNA

  1. XR_008547125.2 RNA Sequence

  2. XR_010155346.1 RNA Sequence

Nucleotide Protein
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