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KAT2B lysine acetyltransferase 2B [ Pan troglodytes (chimpanzee) ]

Gene ID: 460219, updated on 29-Mar-2024

Summary

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Official Symbol
KAT2Bprovided by VGNC
Official Full Name
lysine acetyltransferase 2Bprovided by VGNC
Primary source
VGNC:VGNC:7977
Locus tag
CK820_G0008876
See related
Ensembl:ENSPTRG00000014685
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
PCAF
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (24034061..24148196)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (24033726..24154248)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134809431 Neighboring gene protein phosphatase 2C like domain containing 1 Neighboring gene large ribosomal subunit protein eL39-like Neighboring gene shugoshin 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3 acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of ATAC complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone acetyltransferase KAT2B
Names
K(lysine) acetyltransferase 2B
p300/CBP-associated factor
XP_009443293.2
XP_016796053.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    24034061..24148196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009445018.5 → XP_009443293.2  histone acetyltransferase KAT2B isoform X1

    UniProtKB/TrEMBL
    A0A2I3TV67, A0A2J8NPD1, A0A6D2WWD3, H2QM64, K7BMQ4
    Related
    ENSPTRP00000025331.4
    Conserved Domains (3) summary
    cd05509
    Location:727 → 826
    Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
    COG5076
    Location:487 → 826
    COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    pfam06466
    Location:74 → 325
    PCAF_N; PCAF (P300/CBP-associated factor) N-terminal domain

  2. XM_016940564.4 → XP_016796053.1  histone acetyltransferase KAT2B isoform X2

    UniProtKB/TrEMBL
    A0A2I3TV67
    Related
    ENSPTRP00000093175.1
    Conserved Domains (2) summary
    COG5076
    Location:487 → 652
    COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    pfam06466
    Location:74 → 325
    PCAF_N; PCAF (P300/CBP-associated factor) N-terminal domain
Nucleotide Protein
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