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CAPN7 calpain 7 [ Pan troglodytes (chimpanzee) ]

Gene ID: 460202, updated on 29-Mar-2024

Summary

Official Symbol
CAPN7provided by VGNC
Official Full Name
calpain 7provided by VGNC
Primary source
VGNC:VGNC:1752
Locus tag
CK820_G0008816
See related
Ensembl:ENSPTRG00000014661
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

Location:
chromosome: 3
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (19210014..19256566)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (19209733..19256238)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene small ribosomal subunit protein eS1-like Neighboring gene microRNA mir-548i-2 Neighboring gene collagen alpha-4(VI) chain-like Neighboring gene SH3 domain binding protein 5 Neighboring gene small nucleolar RNA U13 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    19210014..19256566
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009444948.4XP_009443223.1  calpain-7 isoform X1

    See identical proteins and their annotated locations for XP_009443223.1

    UniProtKB/TrEMBL
    A0A2I3SUA6, A0A2J8NP26, A0A6D2WKW9, H2QM47
    Related
    ENSPTRP00000025287.2
    Conserved Domains (4) summary
    smart00720
    Location:687810
    calpain_III; calpain_III domain
    cd00044
    Location:214538
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
    cd02681
    Location:576
    MIT_calpain7_1; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
    cl00299
    Location:85159
    MIT; MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
  2. XM_009444949.5XP_009443224.1  calpain-7 isoform X3

    UniProtKB/TrEMBL
    A0A2I3SUA6
    Conserved Domains (3) summary
    smart00720
    Location:643766
    calpain_III; calpain_III domain
    cd00044
    Location:170494
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
    cl00299
    Location:41115
    MIT; MIT: domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...
  3. XM_063805471.1XP_063661541.1  calpain-7 isoform X5

  4. XM_016940552.4XP_016796041.1  calpain-7 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SUA6
  5. XM_009444950.5XP_009443225.1  calpain-7 isoform X4

    UniProtKB/TrEMBL
    A0A2J8NP30
    Conserved Domains (4) summary
    smart00720
    Location:593716
    calpain_III; calpain_III domain
    cd00044
    Location:214538
    CysPc; Calpains, domains IIa, IIb; calcium-dependent cytoplasmic cysteine proteinases, papain-like. Functions in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction.
    cd02681
    Location:576
    MIT_calpain7_1; MIT: domain contained within Microtubule Interacting and Trafficking molecules. This sub-family of MIT domains is found in the nuclear thiol protease PalBH. The molecular function of the MIT domain is unclear.
    cl00299
    Location:85159
    MIT; domain contained within Microtubule Interacting and Trafficking molecules. The MIT domain is found in sorting nexins, the nuclear thiol protease PalBH, the AAA protein spastin and archaebacterial proteins with similar domain architecture, vacuolar ...