STAT1 signal transducer and activator of transcription 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: STAT1provided by VGNC
Official Full Name: signal transducer and activator of transcription 1provided by VGNC
Primary source: VGNC:VGNC:2869
Locus tag: CK820_G0014689
See related: Ensembl:ENSPTRG00000012749
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2B

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	13	NC_072411.2 (93034085..93079342, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	2B	NC_072400.1 (93033936..93082378, complement)

Chromosome 13 - NC_072411.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

STAT1_425 (e-PCR)
- UniSTS:277772

RH36288 (e-PCR)
- UniSTS:2578

STS-N69004 (e-PCR)
- UniSTS:56649

RH120206 (e-PCR)
- UniSTS:133199

G67903 (e-PCR)
- UniSTS:225635

G67906 (e-PCR)
- UniSTS:225636

G67907 (e-PCR)
- UniSTS:225637

G67904 (e-PCR)
- UniSTS:225638

G67905 (e-PCR)
- UniSTS:225639

G67909 (e-PCR)
- UniSTS:225640

G67911 (e-PCR)
- UniSTS:225641

G67908 (e-PCR)
- UniSTS:225642

G67910 (e-PCR)
- UniSTS:225643

G67912 (e-PCR)
- UniSTS:225644

G67913 (e-PCR)
- UniSTS:225645

G67914 (e-PCR)
- UniSTS:225646

RH78038 (e-PCR)
- UniSTS:13214

PMC55319P3 (e-PCR)
- UniSTS:273321

RH17878 (e-PCR)
- UniSTS:6628

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT	IEA Inferred from Electronic Annotation more info	PubMed
involved_in defense response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to peptide hormone	IEA Inferred from Electronic Annotation more info	PubMed
involved_in type I interferon-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: signal transducer and activator of transcription 1-alpha/beta

Names: signal transducer and activator of transcription 1, 91kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

93034085..93079342 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016950217.3 → XP_016805706.1 signal transducer and activator of transcription 1-alpha/beta isoform X2

UniProtKB/TrEMBL

A0A2I3TNY5, A0A2J8N4G6, A0A6D2XK16, H2QJ60, K7BS59

Related

ENSPTRP00000021795.4

Conserved Domains (5) summary

cd10372
Location:557 → 707

SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins

smart00964
Location:2 → 121

STAT_int; STAT protein, protein interaction domain

cd16851
Location:138 → 313

STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)

cd16845
Location:317 → 477

STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)

pfam12162
Location:715 → 739

STAT1_TAZ2bind; STAT1 TAZ2 binding domain
XM_016950218.4 → XP_016805707.1 signal transducer and activator of transcription 1-alpha/beta isoform X2

UniProtKB/TrEMBL

A0A2I3TNY5, A0A2J8N4G6, A0A6D2XK16, H2QJ60, K7BS59

Related

ENSPTRP00000090934.1

Conserved Domains (5) summary

cd10372
Location:557 → 707

SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins

smart00964
Location:2 → 121

STAT_int; STAT protein, protein interaction domain

cd16851
Location:138 → 313

STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)

cd16845
Location:317 → 477

STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)

pfam12162
Location:715 → 739

STAT1_TAZ2bind; STAT1 TAZ2 binding domain
XM_063791403.1 → XP_063647473.1 signal transducer and activator of transcription 1-alpha/beta isoform X1