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PDK1 pyruvate dehydrogenase kinase 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 459743, updated on 29-Mar-2024

Summary

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Official Symbol
PDK1provided by VGNC
Official Full Name
pyruvate dehydrogenase kinase 1provided by VGNC
Primary source
VGNC:VGNC:6370
Locus tag
CK820_G0001488
See related
Ensembl:ENSPTRG00000012642
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2B
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (74603823..74772969)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (74603797..74765158)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107973828 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC104005263 Neighboring gene integrin subunit alpha 6 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC107973830 Neighboring gene Rap guanine nucleotide exchange factor 4 Neighboring gene mitogen-activated protein kinase kinase kinase 20 Neighboring gene uncharacterized LOC129143420

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial; pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial
Names
pyruvate dehydrogenase kinase, isozyme 1
XP_001147224.2
XP_009442041.1
XP_515910.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    74603823..74772969
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_515910.8 → XP_515910.3  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X3

    See identical proteins and their annotated locations for XP_515910.3

    UniProtKB/TrEMBL
    A0A2J8PQY5, A0A6D2WTQ5, H2QIZ6
    Related
    ENSPTRP00000021603.4
    Conserved Domains (2) summary
    smart00387
    Location:270 → 390
    HATPase_c; Histidine kinase-like ATPases
    pfam10436
    Location:56 → 220
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

  2. XM_009443766.5 → XP_009442041.1  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X1

    Conserved Domains (3) summary
    smart00387
    Location:290 → 411
    HATPase_c; Histidine kinase-like ATPases
    COG0642
    Location:279 → 411
    BaeS; Signal transduction histidine kinase [Signal transduction mechanisms]
    pfam10436
    Location:56 → 240
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

  3. XM_001147224.7 → XP_001147224.2  pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2

    See identical proteins and their annotated locations for XP_001147224.2

    UniProtKB/TrEMBL
    A0A2I3RKX1, A0A2J8PQZ1, A0A6D2XMI8
    Related
    ENSPTRP00000065011.1
    Conserved Domains (2) summary
    smart00387
    Location:290 → 410
    HATPase_c; Histidine kinase-like ATPases
    pfam10436
    Location:56 → 240
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase

RNA

  1. XR_010150152.1 RNA Sequence

  2. XR_010150149.1 RNA Sequence

  3. XR_010150153.1 RNA Sequence

  4. XR_010150150.1 RNA Sequence

  5. XR_010150151.1 RNA Sequence

  6. XR_010150147.1 RNA Sequence

  7. XR_010150148.1 RNA Sequence

  8. XR_010150140.1 RNA Sequence

  9. XR_008546826.2 RNA Sequence

  10. XR_001716307.3 RNA Sequence

  11. XR_008546819.2 RNA Sequence

  12. XR_010150135.1 RNA Sequence

  13. XR_001716308.4 RNA Sequence

  14. XR_001716309.4 RNA Sequence

  15. XR_008546823.2 RNA Sequence

  16. XR_008546831.2 RNA Sequence

  17. XR_008546824.2 RNA Sequence

  18. XR_010150137.1 RNA Sequence

  19. XR_010150138.1 RNA Sequence

  20. XR_008546828.2 RNA Sequence

  21. XR_010150139.1 RNA Sequence

  22. XR_010150154.1 RNA Sequence

  23. XR_001716303.4 RNA Sequence

  24. XR_678509.4 RNA Sequence

  25. XR_001716306.3 RNA Sequence

  26. XR_008546825.2 RNA Sequence

  27. XR_008546830.2 RNA Sequence

  28. XR_001716311.4 RNA Sequence

  29. XR_678508.5 RNA Sequence

  30. XR_010150136.1 RNA Sequence

  31. XR_008546827.2 RNA Sequence

  32. XR_678510.5 RNA Sequence

  33. XR_010150145.1 RNA Sequence

  34. XR_010150155.1 RNA Sequence

  35. XR_010150144.1 RNA Sequence

  36. XR_008546838.2 RNA Sequence

  37. XR_008546836.2 RNA Sequence

  38. XR_008546835.2 RNA Sequence

  39. XR_678511.4 RNA Sequence

  40. XR_008546834.2 RNA Sequence

  41. XR_008546833.2 RNA Sequence

  42. XR_010150146.1 RNA Sequence

  43. XR_010150143.1 RNA Sequence

  44. XR_008546837.2 RNA Sequence

  45. XR_010150141.1 RNA Sequence

  46. XR_010150142.1 RNA Sequence

  47. XR_008546832.2 RNA Sequence

Nucleotide Protein
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