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GRB14 growth factor receptor bound protein 14 [ Pan troglodytes (chimpanzee) ]

Gene ID: 459695, updated on 29-Mar-2024

Summary

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Official Symbol
GRB14provided by VGNC
Official Full Name
growth factor receptor bound protein 14provided by VGNC
Primary source
VGNC:VGNC:1952
Locus tag
CK820_G0001383
See related
Ensembl:ENSPTRG00000012587
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2B
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (66526316..66655444, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (66526276..66655469, complement)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107973712 Neighboring gene fidgetin, microtubule severing factor Neighboring gene small nucleolar RNA SNORA70 Neighboring gene cordon-bleu WH2 repeat protein like 1 Neighboring gene small nucleolar RNA U3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
growth factor receptor-bound protein 14

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    66526316..66655444 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054679091.2 → XP_054535066.1  growth factor receptor-bound protein 14 isoform X4

  2. XM_515864.9 → XP_515864.3  growth factor receptor-bound protein 14 isoform X2

    UniProtKB/TrEMBL
    A0A2I3SJQ3, A0A2J8PQ64, A0A6D2XJN4, H2QIW7, K7DBZ2
    Related
    ENSPTRP00000021504.5
    Conserved Domains (4) summary
    cd10414
    Location:433 → 540
    SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
    cd01259
    Location:230 → 351
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16139
    Location:107 → 191
    RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
    pfam08947
    Location:370 → 414
    BPS; BPS (Between PH and SH2)

  3. XM_054679090.2 → XP_054535065.1  growth factor receptor-bound protein 14 isoform X3

  4. XM_054679089.2 → XP_054535064.1  growth factor receptor-bound protein 14 isoform X1

  5. XM_009443602.3 → XP_009441877.1  growth factor receptor-bound protein 14 isoform X5

    See identical proteins and their annotated locations for XP_009441877.1

    Conserved Domains (4) summary
    cd10414
    Location:346 → 453
    SH2_Grb14; Src homology 2 (SH2) domain found in the growth factor receptor bound, subclass 14 (Grb14) proteins
    cd01259
    Location:143 → 264
    PH_APBB1IP; Amyloid beta (A4) Precursor protein-Binding, family B, member 1 Interacting Protein pleckstrin homology (PH) domain
    cd16139
    Location:20 → 104
    RA_GRB14; Ras-associating (RA) domain found in growth factor receptor-bound (Grb) protein 14
    pfam08947
    Location:283 → 327
    BPS; BPS (Between PH and SH2)
Nucleotide Protein
Heading Accession and Version

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