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ITGB6 integrin subunit beta 6 [ Pan troglodytes (chimpanzee) ]

Gene ID: 459683, updated on 3-Apr-2024

Summary

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Official Symbol
ITGB6provided by VGNC
Official Full Name
integrin subunit beta 6provided by VGNC
Primary source
VGNC:VGNC:52100
Locus tag
CK820_G0001341
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2B
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 13 NC_072411.2 (62150615..62324903, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2B NC_072400.1 (62150604..62324892, complement)

Chromosome 13 - NC_072411.2Genomic Context describing neighboring genes Neighboring gene phospholipase A2 receptor 1 Neighboring gene elongin-B-like Neighboring gene RNA binding motif single stranded interacting protein 1 Neighboring gene ATP-dependent RNA helicase DDX18-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin alphav-beta6 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin beta-6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    62150615..62324903 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024354918.2 → XP_024210686.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  2. XM_024354914.2 → XP_024210682.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  3. XM_024354917.2 → XP_024210685.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  4. XM_054679066.1 → XP_054535041.1  integrin beta-6 isoform X5

  5. XM_024354921.2 → XP_024210689.1  integrin beta-6 isoform X2

    UniProtKB/TrEMBL
    A0A2J8PQ00, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:5 → 412
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:504 → 532
    EGF_2; EGF-like domain
    pfam07965
    Location:582 → 664
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:691 → 733
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  6. XM_024354919.2 → XP_024210687.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  7. XM_024354913.2 → XP_024210681.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  8. XM_024354916.2 → XP_024210684.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  9. XM_054679064.1 → XP_054535039.1  integrin beta-6 isoform X2

    UniProtKB/TrEMBL
    A0A2J8PQ00

  10. XM_024354915.2 → XP_024210683.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain

  11. XM_024354925.2 → XP_024210693.1  integrin beta-6 isoform X3

    UniProtKB/TrEMBL
    A0A2J8PQ03, K7DT99
    Conserved Domains (4) summary
    pfam07974
    Location:451 → 479
    EGF_2; EGF-like domain
    pfam07965
    Location:529 → 611
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:638 → 680
    Integrin_b_cyt; Integrin beta cytoplasmic domain
    cl00057
    Location:21 → 359
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

  12. XM_054679063.1 → XP_054535038.1  integrin beta-6 isoform X2

    UniProtKB/TrEMBL
    A0A2J8PQ00

  13. XM_054679065.1 → XP_054535040.1  integrin beta-6 isoform X4

    UniProtKB/TrEMBL
    A0A2J8PQ07

  14. XM_063791268.1 → XP_063647338.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05

  15. XM_024354920.3 → XP_024210688.1  integrin beta-6 isoform X1

    UniProtKB/TrEMBL
    A0A2J8PQ05, K7DT99
    Conserved Domains (4) summary
    smart00187
    Location:30 → 454
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
    pfam07974
    Location:546 → 574
    EGF_2; EGF-like domain
    pfam07965
    Location:624 → 706
    Integrin_B_tail; Integrin beta tail domain
    pfam08725
    Location:733 → 775
    Integrin_b_cyt; Integrin beta cytoplasmic domain
Nucleotide Protein
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