GLI2 GLI family zinc finger 2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: GLI2provided by VGNC
Official Full Name: GLI family zinc finger 2provided by VGNC
Primary source: VGNC:VGNC:442
Locus tag: CK820_G0024282
See related: Ensembl:ENSPTRG00000012413
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2B

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	13	NC_072411.2 (21419078..21676284)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	2B	NC_072400.1 (21419076..21676282)

Chromosome 13 - NC_072411.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

WI-10818 (e-PCR)
- UniSTS:2058

Gli2 (e-PCR), detects polymorphism
- UniSTS:265490

RH68635 (e-PCR)
- UniSTS:73524

G60419 (e-PCR)
- UniSTS:137525

D2S283 (e-PCR), detects polymorphism
- UniSTS:878

SHGC-105013 (e-PCR)
- UniSTS:169084

D2S2265 (e-PCR), detects polymorphism
- UniSTS:55677

D2S2260 (e-PCR)
- UniSTS:22656

RH92671 (e-PCR)
- UniSTS:86701

SHGC-83341 (e-PCR)
- UniSTS:101046

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in smoothened signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: zinc finger protein GLI2

Names: GLI-Kruppel family member GLI2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072411.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

21419078..21676284

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001158280.7 → XP_001158280.2 zinc finger protein GLI2 isoform X1

See identical proteins and their annotated locations for XP_001158280.2

UniProtKB/TrEMBL

A0A2I3SWC0, A0A2J8M1T8, A0A6D2VYR7, H2R078

Related

ENSPTRP00000040313.3

Conserved Domains (3) summary

COG5189
Location:500 → 590

SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

sd00017
Location:506 → 528

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam09606
Location:1118 → 1504

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
XM_009443195.4 → XP_009441470.1 zinc finger protein GLI2 isoform X2

UniProtKB/TrEMBL

A0A2I3SWC0

Conserved Domains (2) summary

sd00017
Location:489 → 511

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:503 → 530

zf-H2C2_2; Zinc-finger double domain
XM_009443196.4 → XP_009441471.1 zinc finger protein GLI2 isoform X3

See identical proteins and their annotated locations for XP_009441471.1

UniProtKB/TrEMBL

A0A2I3SWC0

Related

ENSPTRP00000080878.1

Conserved Domains (2) summary

sd00017
Location:440 → 462

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:454 → 481

zf-H2C2_2; Zinc-finger double domain
XM_009443194.5 → XP_009441469.1 zinc finger protein GLI2 isoform X1

See identical proteins and their annotated locations for XP_009441469.1

UniProtKB/TrEMBL

A0A2I3SWC0, A0A2J8M1T8, A0A6D2VYR7, H2R078

Conserved Domains (3) summary

COG5189
Location:500 → 590

SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]

sd00017
Location:506 → 528

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam09606
Location:1118 → 1504

Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
XM_063790378.1 → XP_063646448.1 zinc finger protein GLI2 isoform X3