PAX8 paired box 8 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: PAX8provided by VGNC
Official Full Name: paired box 8provided by VGNC
Primary source: VGNC:VGNC:10736
Locus tag: CK820_G0052769
See related: Ensembl:ENSPTRG00000012380
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2A

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	12	NC_072410.2 (10060189..10119633)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	2A	NC_072399.1 (112379358..112438802, complement)

Chromosome 12 - NC_072410.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

RH45733 (e-PCR)
- UniSTS:79616

D8S2279 (e-PCR)
- UniSTS:473907

PAX8__1200 (e-PCR)
- UniSTS:277556

PAX8__v328 (e-PCR)
- UniSTS:277556

WI-19770 (e-PCR)
- UniSTS:28488

RH94024 (e-PCR)
- UniSTS:89437

RH79182 (e-PCR)
- UniSTS:31336

D10S16 (e-PCR)
- UniSTS:155756

D11Bir2 (e-PCR), detects polymorphism
- UniSTS:141710

RH80705 (e-PCR)
- UniSTS:85135

D16S325 (e-PCR)
- UniSTS:147089

SHGC-52928 (e-PCR)
- UniSTS:64915

D2S1597E (e-PCR)
- UniSTS:150681

D22S296 (e-PCR)
- UniSTS:147641

D2S1963 (e-PCR)
- UniSTS:67546

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in anatomical structure development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: paired box protein Pax-8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

10060189..10119633

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016949285.4 → XP_016804774.1 paired box protein Pax-8 isoform X3

UniProtKB/TrEMBL

H2R8M9

Conserved Domains (2) summary

smart00351
Location:9 → 134

PAX; Paired Box domain

pfam12403
Location:344 → 406

Pax2_C; Paired-box protein 2 C terminal
XM_054678204.2 → XP_054534179.1 paired box protein Pax-8 isoform X6
XM_016949283.3 → XP_016804772.1 paired box protein Pax-8 isoform X1

UniProtKB/TrEMBL

H2R8M9

Conserved Domains (2) summary

smart00351
Location:9 → 134

PAX; Paired Box domain

pfam12403
Location:344 → 455

Pax2_C; Paired-box protein 2 C terminal
XM_016949284.3 → XP_016804773.1 paired box protein Pax-8 isoform X2

UniProtKB/TrEMBL

A0A2I3T8H6, A0A2J8IVS0, A0A6D2XGB8, H2R8M9

Related

ENSPTRP00000085551.1

Conserved Domains (2) summary

smart00351
Location:9 → 133

PAX; Paired Box domain

pfam12403
Location:343 → 454

Pax2_C; Paired-box protein 2 C terminal
XM_016949287.3 → XP_016804776.1 paired box protein Pax-8 isoform X5

UniProtKB/TrEMBL

A0A2J8IVR1

Conserved Domains (1) summary

smart00351
Location:9 → 133

PAX; Paired Box domain
XM_016949286.4 → XP_016804775.1 paired box protein Pax-8 isoform X4