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EPAS1 endothelial PAS domain protein 1 [ Pan troglodytes (chimpanzee) ]

Gene ID: 459204, updated on 3-Dec-2024

Summary

Official Symbol
EPAS1provided by VGNC
Official Full Name
endothelial PAS domain protein 1provided by VGNC
Primary source
VGNC:VGNC:244
Locus tag
CK820_G0028031
See related
Ensembl:ENSPTRG00000011891
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
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Genomic context

See EPAS1 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 12 NC_072410.2 (76322056..76411394, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 2A NC_072399.1 (46441855..46531179)

Chromosome 12 - NC_072410.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104004964 Neighboring gene uncharacterized LOC134807820 Neighboring gene protein kinase C epsilon Neighboring gene uncharacterized LOC134807919 Neighboring gene uncharacterized LOC134807918

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in cytoplasm PubMed 
located_in nucleus PubMed 
part_of transcription regulator complex PubMed 

General protein information

Preferred Names
endothelial PAS domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    76322056..76411394 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001147219.7XP_001147219.1  endothelial PAS domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_001147219.1

    UniProtKB/TrEMBL
    A0A2I3TA92, A0A2J8LL81, A0A6D2VU71, H2QHV1
    Related
    ENSPTRP00000020413.4
    Conserved Domains (5) summary
    smart00091
    Location:86147
    PAS; PAS domain
    cd00083
    Location:1268
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam08778
    Location:833869
    HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain
    pfam08447
    Location:254341
    PAS_3; PAS fold
    pfam11413
    Location:518549
    HIF-1; Hypoxia-inducible factor-1
  2. XM_054677824.2XP_054533799.1  endothelial PAS domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A2I3TA92
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