SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: SOS1provided by VGNC
Official Full Name: SOS Ras/Rac guanine nucleotide exchange factor 1provided by VGNC
Primary source: VGNC:VGNC:6658
Locus tag: CK820_G0027932
See related: Ensembl:ENSPTRG00000011857
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2A

Exon count:: 24

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	12	NC_072410.2 (83655379..83798295)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	2A	NC_072399.1 (39054941..39194110, complement)

Chromosome 12 - NC_072410.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

A009Y37 (e-PCR)
- UniSTS:63772

RH69513 (e-PCR)
- UniSTS:1314

RH68727 (e-PCR)
- UniSTS:44838

RH36309 (e-PCR)
- UniSTS:561

WI-21651 (e-PCR)
- UniSTS:48442

G32992 (e-PCR)
- UniSTS:117569

RH69415 (e-PCR)
- UniSTS:59731

SHGC-37149 (e-PCR)
- UniSTS:40299

RH48741 (e-PCR)
- UniSTS:71800

RH98865 (e-PCR)
- UniSTS:93054

G33055 (e-PCR)
- UniSTS:117631

SGC31905 (e-PCR)
- UniSTS:62609

SGC34493 (e-PCR)
- UniSTS:47019

AI449023 (e-PCR)
- UniSTS:160701

D2S1690E (e-PCR)
- UniSTS:150718

RH98720 (e-PCR)
- UniSTS:89545

SHGC-31981 (e-PCR)
- UniSTS:40652

D2S235E (e-PCR)
- UniSTS:473061

PMC155645P1 (e-PCR)
- UniSTS:271343

A010A36 (e-PCR)
- UniSTS:32759

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein heterodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Ras protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: son of sevenless homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072410.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

83655379..83798295

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063789973.1 → XP_063646043.1 son of sevenless homolog 1 isoform X7
XM_515425.7 → XP_515425.5 son of sevenless homolog 1 isoform X1

UniProtKB/TrEMBL

K7CI68
XM_009442353.3 → XP_009440628.3 son of sevenless homolog 1 isoform X2
XM_009442356.4 → XP_009440631.3 son of sevenless homolog 1 isoform X5
XM_009442354.4 → XP_009440629.3 son of sevenless homolog 1 isoform X3
XM_016948386.3 → XP_016803875.2 son of sevenless homolog 1 isoform X4
XM_009442357.5 → XP_009440632.3 son of sevenless homolog 1 isoform X6