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LIMK2 LIM domain kinase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 458970, updated on 3-Apr-2024

Summary

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Official Symbol
LIMK2provided by VGNC
Official Full Name
LIM domain kinase 2provided by VGNC
Primary source
VGNC:VGNC:53399
Locus tag
CK820_G0024553
See related
Ensembl:ENSPTRG00000014266
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 23 NC_086016.1 (33331063..33399268)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 22 NC_072420.1 (26363495..26431666)

Chromosome 23 - NC_086016.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein-associated protein N-like Neighboring gene ring finger protein 185 Neighboring gene U6 spliceosomal RNA Neighboring gene phosphoinositide-3-kinase interacting protein 1 Neighboring gene POZ/BTB and AT hook containing zinc finger 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LIM domain kinase 2
XP_016794483.1
XP_016794484.1
XP_016794487.1
XP_016794489.1
XP_024208624.1
XP_054531837.1
XP_063664221.1
XP_063664222.1
XP_063664223.1
XP_063664224.1
XP_063664226.1
XP_063664227.1
XP_063664228.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    33331063..33399268
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016938994.3 → XP_016794483.1  LIM domain kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A2J8QNZ2, A0A6D2WGC5, K7CB54, K7D809
    Related
    ENSPTRP00000080356.1
    Conserved Domains (4) summary
    cd09463
    Location:12 → 65
    LIM1_LIMK2; The first LIM domain of LIMK2 (LIM domain Kinase 2)
    cd09465
    Location:67 → 125
    LIM2_LIMK2; The second LIM domain of LIMK2 (LIM domain Kinase 2)
    cd14222
    Location:337 → 608
    STKc_LIMK2; Catalytic domain of the Serine/Threonine Kinase, LIM domain kinase 2
    pfam00595
    Location:152 → 236
    PDZ; PDZ domain (Also known as DHR or GLGF)

  2. XM_016938995.3 → XP_016794484.1  LIM domain kinase 2 isoform X3

    UniProtKB/TrEMBL
    K7CB54
    Conserved Domains (5) summary
    cd09463
    Location:12 → 65
    LIM1_LIMK2; The first LIM domain of LIMK2 (LIM domain Kinase 2)
    cd09465
    Location:67 → 125
    LIM2_LIMK2; The second LIM domain of LIMK2 (LIM domain Kinase 2)
    smart00221
    Location:334 → 579
    STYKc; Protein kinase; unclassified specificity
    pfam00595
    Location:152 → 236
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl21453
    Location:337 → 586
    PKc_like; Protein Kinases, catalytic domain

  3. XM_016939000.3 → XP_016794489.1  LIM domain kinase 2 isoform X6

    UniProtKB/TrEMBL
    K7CB54
    Conserved Domains (4) summary
    cd09465
    Location:67 → 125
    LIM2_LIMK2; The second LIM domain of LIMK2 (LIM domain Kinase 2)
    smart00221
    Location:233 → 500
    STYKc; Protein kinase; unclassified specificity
    cd14222
    Location:236 → 507
    STKc_LIMK2; Catalytic domain of the Serine/Threonine Kinase, LIM domain kinase 2
    cl02475
    Location:12 → 65
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  4. XM_063808158.1 → XP_063664228.1  LIM domain kinase 2 isoform X7

  5. XM_016938998.3 → XP_016794487.1  LIM domain kinase 2 isoform X4

    UniProtKB/TrEMBL
    A0A2I3RSS8, K7BV05
    Related
    ENSPTRP00000079896.1

  6. XM_063808151.1 → XP_063664221.1  LIM domain kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8QNZ6, A0A6D2W9Z6, K7DJP5

  7. XM_063808157.1 → XP_063664227.1  LIM domain kinase 2 isoform X5

  8. XM_063808156.1 → XP_063664226.1  LIM domain kinase 2 isoform X4

    UniProtKB/TrEMBL
    A0A2I3RSS8

  9. XM_063808153.1 → XP_063664223.1  LIM domain kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8QNZ6, A0A6D2W9Z6, K7DJP5

  10. XM_054675862.2 → XP_054531837.1  LIM domain kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8QNZ6, A0A6D2W9Z6, K7DJP5

  11. XM_063808154.1 → XP_063664224.1  LIM domain kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8QNZ6, A0A6D2W9Z6, K7DJP5

  12. XM_063808152.1 → XP_063664222.1  LIM domain kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8QNZ6, A0A6D2W9Z6, K7DJP5

  13. XM_024352856.2 → XP_024208624.1  LIM domain kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8QNZ6, A0A6D2W9Z6, K7BV05, K7DJP5
    Conserved Domains (4) summary
    cd09465
    Location:46 → 104
    LIM2_LIMK2; The second LIM domain of LIMK2 (LIM domain Kinase 2)
    cd14222
    Location:316 → 587
    STKc_LIMK2; Catalytic domain of the Serine/Threonine Kinase, LIM domain kinase 2
    pfam00595
    Location:131 → 215
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl02475
    Location:15 → 44
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

RNA

  1. XR_010156111.1 RNA Sequence

  2. XR_001712634.3 RNA Sequence

  3. XR_010156116.1 RNA Sequence

  4. XR_010156115.1 RNA Sequence

  5. XR_010156114.1 RNA Sequence

  6. XR_010156112.1 RNA Sequence

  7. XR_010156113.1 RNA Sequence

Nucleotide Protein
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