RBX1 ring-box 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: RBX1provided by VGNC
Official Full Name: ring-box 1provided by VGNC
Primary source: VGNC:VGNC:9926
Locus tag: CK820_G0027549
See related: Ensembl:ENSPTRG00000014417
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	23	NC_086016.1 (42942702..42964014)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	22	NC_072420.1 (35975128..35996409)

Chromosome 23 - NC_086016.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

D8S2279 (e-PCR)
- UniSTS:473907

D15S1477 (e-PCR)
- UniSTS:474482

SHGC-34633 (e-PCR)
- UniSTS:25483

D16S325 (e-PCR)
- UniSTS:147089

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables cullin family protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in ubiquitin-dependent protein catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cullin-RING ubiquitin ligase complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase RBX1

Names: ring-box 1, E3 ubiquitin protein ligase

XP_063663986.1

EC 2.3.2.27

EC 2.3.2.32

XP_515153.2

EC 2.3.2.27

EC 2.3.2.32

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

42942702..42964014

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_515153.7 → XP_515153.2 E3 ubiquitin-protein ligase RBX1 isoform X1

See identical proteins and their annotated locations for XP_515153.2

UniProtKB/TrEMBL

A0A2J8LN90, A0A6D2XR06, H2QLR9

Related

ENSPTRP00000024839.2

Conserved Domains (1) summary

cd16485
Location:40 → 101

mRING-H2-C3H2C2D_RBX1; modified RING finger, H2 subclass (C3H2C2D-type), found in RING-box protein 1 (RBX1) and similar proteins
XM_063807916.1 → XP_063663986.1 E3 ubiquitin-protein ligase RBX1 isoform X2