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CHEK2 checkpoint kinase 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 458733, updated on 3-Apr-2024

Summary

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Official Symbol
CHEK2provided by VGNC
Official Full Name
checkpoint kinase 2provided by VGNC
Primary source
VGNC:VGNC:12828
Locus tag
CK820_G0024446
See related
Ensembl:ENSPTRG00000014206
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 23 NC_086016.1 (30842111..30896534, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 22 NC_072420.1 (23874510..23929003, complement)

Chromosome 23 - NC_086016.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC129138472 Neighboring gene tetratricopeptide repeat domain 28 Neighboring gene small nucleolar RNA SNORD42 Neighboring gene coiled-coil domain containing 117 Neighboring gene HscB mitochondrial iron-sulfur cluster cochaperone Neighboring gene X-box binding protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase Chk2
Names
CHK2 checkpoint homolog
protein kinase CHK2
XP_016794370.2
XP_016794371.2
XP_016794372.2
XP_016794373.2
XP_016794374.2
XP_016794375.2
XP_016794376.2
XP_016794377.2
XP_016794378.1
XP_063663710.1
XP_063663711.1
XP_063663712.1
XP_063663713.1
XP_063663714.1
XP_063663715.1
XP_063663716.1
XP_063663717.1
XP_063663718.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    30842111..30896534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016938886.3 → XP_016794375.2  serine/threonine-protein kinase Chk2 isoform X6

    UniProtKB/TrEMBL
    K7D8Y1

  2. XM_063807644.1 → XP_063663714.1  serine/threonine-protein kinase Chk2 isoform X7

  3. XM_016938887.3 → XP_016794376.2  serine/threonine-protein kinase Chk2 isoform X9

  4. XM_016938885.3 → XP_016794374.2  serine/threonine-protein kinase Chk2 isoform X5

  5. XM_016938883.3 → XP_016794372.2  serine/threonine-protein kinase Chk2 isoform X3

  6. XM_016938884.3 → XP_016794373.2  serine/threonine-protein kinase Chk2 isoform X4

  7. XM_016938881.3 → XP_016794370.2  serine/threonine-protein kinase Chk2 isoform X1

  8. XM_063807641.1 → XP_063663711.1  serine/threonine-protein kinase Chk2 isoform X5

  9. XM_063807646.1 → XP_063663716.1  serine/threonine-protein kinase Chk2 isoform X8

  10. XM_016938888.3 → XP_016794377.2  serine/threonine-protein kinase Chk2 isoform X10

  11. XM_016938882.3 → XP_016794371.2  serine/threonine-protein kinase Chk2 isoform X2

  12. XM_063807648.1 → XP_063663718.1  serine/threonine-protein kinase Chk2 isoform X11

  13. XM_016938889.3 → XP_016794378.1  serine/threonine-protein kinase Chk2 isoform X11

    UniProtKB/TrEMBL
    A0A2J8QN66
    Conserved Domains (2) summary
    smart00220
    Location:3 → 265
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14084
    Location:1 → 265
    STKc_Chk2; Catalytic domain of the Serine/Threonine kinase, Cell cycle Checkpoint Kinase 2

  14. XM_063807643.1 → XP_063663713.1  serine/threonine-protein kinase Chk2 isoform X6

    UniProtKB/TrEMBL
    K7D8Y1

  15. XM_063807647.1 → XP_063663717.1  serine/threonine-protein kinase Chk2 isoform X10

  16. XM_063807642.1 → XP_063663712.1  serine/threonine-protein kinase Chk2 isoform X5

  17. XM_063807645.1 → XP_063663715.1  serine/threonine-protein kinase Chk2 isoform X7

  18. XM_063807640.1 → XP_063663710.1  serine/threonine-protein kinase Chk2 isoform X2

Nucleotide Protein
Heading Accession and Version

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