MAPK1 mitogen-activated protein kinase 1 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: MAPK1provided by VGNC
Official Full Name: mitogen-activated protein kinase 1provided by VGNC
Primary source: VGNC:VGNC:12896
Locus tag: CK820_G0053002
See related: Ensembl:ENSPTRG00000014120
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	23	NC_086016.1 (23711703..23818926, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	22	NC_072420.1 (16746369..16851289, complement)

Chromosome 23 - NC_086016.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Collectively, our results demonstrate that PGE(2) at physiologically relevant concentrations induces COX-2 expression in human NPE cells via activation of EP(2)- and EP(4) receptors and phosphorylation of p38 and p42/44 MAPKs.
Title: Prostaglandin E2 induces cyclooxygenase-2 expression in human non-pigmented ciliary epithelial cells through activation of p38 and p42/44 mitogen-activated protein kinases.

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Pathways from PubChem

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General gene information

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Markers

D22S1011E (e-PCR)
- UniSTS:150799

D22S1022E (e-PCR)
- UniSTS:150803

SHGC-172572 (e-PCR)
- UniSTS:183602

G30303 (e-PCR)
- UniSTS:81521

RH47000 (e-PCR)
- UniSTS:34196

Mapk1 (e-PCR), detects polymorphism
- UniSTS:143825

MAPK1_921 (e-PCR)
- UniSTS:277477

MAPK1_V207 (e-PCR)
- UniSTS:277477

SHGC-34055 (e-PCR)
- UniSTS:58607

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables MAP kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: mitogen-activated protein kinase 1

XP_003317171.1

EC 2.7.11.24

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_086016.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

23711703..23818926 complement

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GenBank, FASTA, Sequence Viewer (Graphics)