DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: DYRK1Aprovided by VGNC
Official Full Name: dual specificity tyrosine phosphorylation regulated kinase 1Aprovided by VGNC
Primary source: VGNC:VGNC:7682
Locus tag: CK820_G0022779
See related: Ensembl:ENSPTRG00000013901
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	22	NC_072420.2 (38069187..38218400)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	21	NC_072419.1 (35721946..35871158)

Chromosome 22 - NC_072420.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

SHGC-51948 (e-PCR)
- UniSTS:26628

D21S270 (e-PCR), detects polymorphism
- UniSTS:41735

STS-G06294 (e-PCR)
- UniSTS:10505

RH120501 (e-PCR)
- UniSTS:133666

DYRK1A__4795 (e-PCR)
- UniSTS:462887

SHGC-63617 (e-PCR)
- UniSTS:43866

SHGC-50010 (e-PCR)
- UniSTS:5746

D21S1972 (e-PCR)
- UniSTS:378

SHGC-87629 (e-PCR)
- UniSTS:9867

SHGC-87626 (e-PCR)
- UniSTS:67212

SHGC-51949 (e-PCR)
- UniSTS:16022

D21S394 (e-PCR)
- UniSTS:147863

SHGC-170065 (e-PCR)
- UniSTS:173721

D11Wox11 (e-PCR)
- UniSTS:518811

G34602 (e-PCR)
- UniSTS:70325

SHGC-87621 (e-PCR)
- UniSTS:40388

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine/tyrosine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables transcription coactivator activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in peptidyl-serine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-threonine phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein autophosphorylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: dual specificity tyrosine-phosphorylation-regulated kinase 1A

Names: dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

XP_009423116.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_024208111.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_024208113.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_054531045.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_054531046.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_063659745.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_063659746.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_063659747.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_063659748.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_063659749.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

XP_063659750.1

EC 2.7.1.-

EC 2.7.11.23

EC 2.7.12.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072420.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

38069187..38218400

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009424841.5 → XP_009423116.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

See identical proteins and their annotated locations for XP_009423116.1

UniProtKB/TrEMBL

A0A2J8M7T0, A0A6D2WLE2, H2QL08

Related

ENSPTRP00000023923.4

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_063803677.1 → XP_063659747.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X4
XM_063803675.1 → XP_063659745.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3
XM_024352343.3 → XP_024208111.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1

UniProtKB/TrEMBL

A0A2J8M7T0, A0A6D2WLE2, H2QL08

Conserved Domains (1) summary

cd14226
Location:148 → 484

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_024352345.3 → XP_024208113.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X2

UniProtKB/TrEMBL

A0A2J8M7S8, A0A803KGL7, K7DQB0

Conserved Domains (1) summary

cd14226
Location:139 → 475

PKc_DYRK1; Catalytic domain of the protein kinase, Dual-specificity tYrosine-phosphorylated and -Regulated Kinase 1
XM_063803676.1 → XP_063659746.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X4
XM_063803678.1 → XP_063659748.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X4
XM_054675070.2 → XP_054531045.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3
XM_054675071.2 → XP_054531046.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X3
XM_063803679.1 → XP_063659749.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X4
XM_063803680.1 → XP_063659750.1 dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X5