CAPN9 calpain 9 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CAPN9provided by VGNC
Official Full Name: calpain 9provided by VGNC
Primary source: VGNC:VGNC:461
Locus tag: CK820_G0023090
See related: Ensembl:ENSPTRG00000002097
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	1	NC_072398.2 (18385633..18440001, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	1	NC_072398.1 (212883335..212937703)

Chromosome 1 - NC_072398.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Markers

SHGC-148871 (e-PCR)
- UniSTS:176657

G15722 (e-PCR)
- UniSTS:43809

AL009462 (e-PCR)
- UniSTS:19505

SHGC-148285 (e-PCR)
- UniSTS:176299

D1S1656 (e-PCR), detects polymorphism
- UniSTS:58809

D1S3730 (e-PCR)
- UniSTS:31168

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables calcium-dependent cysteine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in proteolysis	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: calpain-9

XP_016796168.2

EC 3.4.22.-

XP_016796178.1

EC 3.4.22.-

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

18385633..18440001 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_016940689.3 → XP_016796178.1 calpain-9 isoform X2

UniProtKB/TrEMBL

A0A2I3T2R0, A0A2J8M6H9, A0A2J8M6I1, A0A6D2WJG9, A0A6D2WYQ5, H2Q1B8

Related

ENSPTRP00000083507.1

Conserved Domains (4) summary

cd00214
Location:321 → 470

Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...

pfam00648
Location:43 → 309

Peptidase_C2; Calpain family cysteine protease

cd15897
Location:496 → 524

EFh_PEF; EF-hand motif [structural motif]

cl25352
Location:496 → 664

EFh_PEF; The penta-EF hand (PEF) family
XM_016940679.3 → XP_016796168.2 calpain-9 isoform X1