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NCSTN nicastrin [ Pan troglodytes (chimpanzee) ]

Gene ID: 457435, updated on 29-Mar-2024

Summary

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Official Symbol
NCSTNprovided by VGNC
Official Full Name
nicastrinprovided by VGNC
Primary source
VGNC:VGNC:1344
Locus tag
CK820_G0049307
See related
Ensembl:ENSPTRG00000001550
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (88842909..88858518, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (142491238..142506823)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene nescient helix-loop-helix 1 Neighboring gene COPI coat complex subunit alpha Neighboring gene small ubiquitin-related modifier 1-like Neighboring gene uncharacterized LOC107968979 Neighboring gene peroxisomal biogenesis factor 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in Notch receptor processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nicastrin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    88842909..88858518 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_513923.7 → XP_513923.2  nicastrin

    See identical proteins and their annotated locations for XP_513923.2

    UniProtKB/TrEMBL
    A0A2I3TWA0, A0A2J8JAG7, A0A6D2XFG8, H2Q0E4
    Related
    ENSPTRP00000002601.3
    Conserved Domains (1) summary
    cd03881
    Location:175 → 482
    M28_Nicastrin; M28 Zn-Peptidase Nicastrin, a main component of gamma-secretase complex
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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